ELTD1: cDNA Clones

ELTD1 encodes a protein composed of a large N-terminal extracellular domain with epidermal growth factor (EGF)-like repeats, a seven-transmembrane domain, and a short cytoplasmic tail. ELTD1 belongs to the secretin family of G protein-coupled peptide hormone receptors and the EGF-TM7 subfamily of receptors. ELTD1 is the first seven-transmembrane receptor containing EGF-like repeats that is developmentally regulated in the heart.