Endothelin ETA Receptor Antagonists: Small Molecules and Peptides
EDNRA and EDNRB (endothelin A and B receptors, respectively) are members of the rhodopsin-like 7-transmembrane receptor family. EDNRA binds endothelins ET-1 and ET-2 preferentially, and is expressed on vascular smooth muscle where it mediates vasoconstriction. EDNRB binds all three endothelin forms equally, and is expressed on endothelial cells where it mediates vasodilation.
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2 results for "Endothelin ETA Receptor Antagonists Small Molecules and Peptides" in Products
Endothelin ETA Receptor Antagonists: Small Molecules and Peptides
EDNRA and EDNRB (endothelin A and B receptors, respectively) are members of the rhodopsin-like 7-transmembrane receptor family. EDNRA binds endothelins ET-1 and ET-2 preferentially, and is expressed on vascular smooth muscle where it mediates vasoconstriction. EDNRB binds all three endothelin forms equally, and is expressed on endothelial cells where it mediates vasodilation.
Selective ETA antagonist
| Purity: | ≥95% (HPLC) |
Selective ETA antagonist
| Chemical Name: | (αS)-α-[(4,6-Dimethyl-2-pyrimidinyl)oxy]-β-methoxy-β-phenylbenzenepropanoic acid |
| Purity: | ≥99% (HPLC) |
