Girdin Products
Girdin (GIRDers of actIN filaments; also APE and GIV) is a member of the CCDC88 family of molecules. It is a cytosolic protein, ubiquitously expressed, and plays a key role in the motility of breast cancer cells. Human Girdin is 1871 amino acids (aa) in length. It contains two coiled-coil regions that mediate homodimerization (aa 196-425 and 458-1358), and one phosphoinositide-binding domain (aa 1390-1408). Normally, Girdin is membrane-associated via an interaction with phosphoinositides. Upon phosphorylation at Ser1417 by Akt, it relocates to lamellipodia where it crosslinks actin filaments. Multiple isoforms of Girdin have been detected.
94 results for "Girdin" in Products
94 results for "Girdin" in Products
Girdin Products
Girdin (GIRDers of actIN filaments; also APE and GIV) is a member of the CCDC88 family of molecules. It is a cytosolic protein, ubiquitously expressed, and plays a key role in the motility of breast cancer cells. Human Girdin is 1871 amino acids (aa) in length. It contains two coiled-coil regions that mediate homodimerization (aa 196-425 and 458-1358), and one phosphoinositide-binding domain (aa 1390-1408). Normally, Girdin is membrane-associated via an interaction with phosphoinositides. Upon phosphorylation at Ser1417 by Akt, it relocates to lamellipodia where it crosslinks actin filaments. Multiple isoforms of Girdin have been detected.
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, Simple Western |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |
![Western Blot: Girdin AntibodyBSA Free [NBP1-76253]](https://resources.bio-techne.com/images/products/Girdin-Antibody-Western-Blot-NBP1-76253-img0001.jpg "Western Blot: Girdin AntibodyBSA Free [NBP1-76253]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #M012 |
| Applications: | IHC, WB, ICC/IF, IP |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Girdin [p Ser1416] Antibody](https://resources.bio-techne.com/images/products/nbp3-23336_rabbit-girdin-p-ser1416-pab-19920231820298.jpg "Western Blot: Girdin [p Ser1416] Antibody [NBP3-23336] -")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Girdin [p Tyr1764] Antibody](https://resources.bio-techne.com/images/products/nbp3-23352_rabbit-girdin-p-tyr1764-pab-19920231856955.jpg "Western Blot: Girdin [p Tyr1764] Antibody [NBP3-23352] -")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Girdin [p Ser1674] Antibody](https://resources.bio-techne.com/images/products/nbp3-23205_rabbit-girdin-p-ser1674-pab-199202317594420.jpg "Western Blot: Girdin [p Ser1674] Antibody [NBP3-23205] -")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
![Immunohistochemistry-Paraffin: Girdin Antibody [NBP2-38387]](https://resources.bio-techne.com/images/products/Girdin-Antibody-Immunohistochemistry-Paraffin-NBP2-38387-img0003.jpg "Immunohistochemistry-Paraffin: Girdin Antibody [NBP2-38387]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
![Western Blot: Girdin Antibody [NBP1-71857]](https://resources.bio-techne.com/images/products/Girdin-Antibody-Western-Blot-NBP1-71857-img0003.jpg "Western Blot: Girdin Antibody [NBP1-71857]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
![Immunohistochemistry: Girdin Antibody [NBP1-90135]](https://resources.bio-techne.com/images/products/Girdin-Antibody-Immunohistochemistry-NBP1-90135-img0003.jpg "Immunohistochemistry: Girdin Antibody [NBP1-90135]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IP, WB (-) |
![Immunoprecipitation: Girdin Antibody [NBP1-71856]](https://resources.bio-techne.com/images/products/Girdin-Antibody-Western-Blot-NBP1-71856-img0002.jpg "Immunoprecipitation: Girdin Antibody [NBP1-71856]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |
| Applications: | AC |
| Applications: | AC |
| Applications: | AC |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IP, WB (-) |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IP, WB (-) |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IP, WB (-) |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |