Glutaminyl-peptide Cyclotransferase/QPCT Products
Glutaminyl-peptide Cyclotransferase, also known as Glutaminyl Cyclase, catalyzes the conversion of N-terminal L-glutaminyl residues of peptides to pyroglutamyl groups. The enzyme is present in the pituitary and adrenal glands, where it is important for the generation of the N-terminal pyroglutamyl groups of peptide hormones such as neurotensin and thyrotropin-releasing hormone. Glutaminyl Cyclase also catalyzes the conversion of N-terminal L-glutamyl residues to pyroglutamyl residues. This activity may contribute to the formation of several amyloid-related plaque forming peptides, contributing to Alzheimer's disease pathology. Glutaminyl Cyclase is also considered to be a diagnostic marker of thyroid tumors.
46 results for "Glutaminyl-peptide Cyclotransferase/QPCT" in Products
46 results for "Glutaminyl-peptide Cyclotransferase/QPCT" in Products
Glutaminyl-peptide Cyclotransferase/QPCT Products
Glutaminyl-peptide Cyclotransferase, also known as Glutaminyl Cyclase, catalyzes the conversion of N-terminal L-glutaminyl residues of peptides to pyroglutamyl groups. The enzyme is present in the pituitary and adrenal glands, where it is important for the generation of the N-terminal pyroglutamyl groups of peptide hormones such as neurotensin and thyrotropin-releasing hormone. Glutaminyl Cyclase also catalyzes the conversion of N-terminal L-glutamyl residues to pyroglutamyl residues. This activity may contribute to the formation of several amyloid-related plaque forming peptides, contributing to Alzheimer's disease pathology. Glutaminyl Cyclase is also considered to be a diagnostic marker of thyroid tumors.
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | IHC |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Immunohistochemistry-Paraffin: Glutaminyl-peptide Cyclotransferase/QPCT Antibody [NBP1-81838]](https://resources.bio-techne.com/images/products/Glutaminyl-peptide-Cyclotransferase-QPCT-Antibody-Immunohistochemistry-Paraffin-NBP1-81838-img0010.jpg "Immunohistochemistry-Paraffin: Glutaminyl-peptide Cyclotransferase/QPCT Antibody [NBP1-81838]")
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #C2 |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: Glutaminyl-peptide Cyclotransferase/QPCT Antibody [NBP1-79295]](https://resources.bio-techne.com/images/products/QPCT-Antibody-Western-Blot-NBP1-79295-img0002.jpg "Western Blot: Glutaminyl-peptide Cyclotransferase/QPCT Antibody [NBP1-79295]")
| Applications: | WB |
![Western Blot: Glutaminyl-peptide Cyclotransferase/QPCT Overexpression Lysate [NBL1-15029]](https://resources.bio-techne.com/images/products/QPCT-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-15029-img0002.jpg "Western Blot: Glutaminyl-peptide Cyclotransferase/QPCT Overexpression Lysate [NBL1-15029]")
| Reactivity: | Human |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #3G2 |
| Applications: | IHC, ELISA |
![Immunohistochemistry-Paraffin: Glutaminyl-peptide Cyclotransferase/QPCT Antibody (3G2) [H00025797-M02]](https://resources.bio-techne.com/images/products/Glutaminyl-peptide-Cyclotransferase-QPCT-Antibody-3G2-Immunohistochemistry-Paraffin-H00025797-M02-img0002.jpg "Immunohistochemistry-Paraffin: Glutaminyl-peptide Cyclotransferase/QPCT Antibody (3G2) [H00025797-M02]")
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ELISA |
![Immunohistochemistry-Paraffin: Glutaminyl-peptide Cyclotransferase/QPCT Antibody [NBP3-00186]](https://resources.bio-techne.com/images/products/Glutaminyl-peptide-Cyclotransferase-QPCT-Antibody-Immunohistochemistry-Paraffin-NBP3-00186-img0002.jpg "Immunohistochemistry-Paraffin: Glutaminyl-peptide Cyclotransferase/QPCT Antibody [NBP3-00186]")
| Applications: | AC |
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #4E11 |
| Applications: | WB, ELISA |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ELISA |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ELISA |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ELISA |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ELISA |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ELISA |
| Source: | Sf 21 (baculovirus) |
| Accession #: | Q16769 |
| Applications: | EnzAct |
Potent glutaminyl cyclase inhibitor; disrupts binding of SIRP-α to CD47
| Chemical Name: | 6'-Fluoro-2-[4-(4-methyl-4H-1,2,4-triazol-3-yl)-1-piperidinyl]-3,3'-bipyridine |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ELISA |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ELISA |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ELISA |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ELISA |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ELISA |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ELISA |