GPR3: cDNA Clones

GPR3, previously called ACCA (adenylate cyclase constitutive activator), is 7-transmembrane receptor that has been shown to promote cAMP accumulation. In oocytes, cAMP generated by GPR3 regulates maintenance of meiotic arrest. GPR3 is also expressed in the brain, where it has been implicated in cAMP-dependent emotional responses and modulation of amyloid-beta peptide generation.