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GPR55 Products

Members of the G protein-coupled receptor (GPCR) family, such as GPR55, play important roles in signal transduction from the external environment to the inside of the cell. GPR55 is a receptor for L-alpha-lysophosphatidylinositol (LPI). LPI induces Ca2+ release from intracellular stores via the heterotrimeric G protein GNA13 and RHOA. GPR55 is expressed in the caudate nucleus and putamen, but not detected in the hippocampus, thalamus, pons cerebellum, frontal cortex of the brain or in the liver. It is expressed in osteoclasts and osteoblasts. GPR55 may play a role in bone physiology by regulating osteoclast number and function. GPR55 may also be involved in hyperalgesia associated with inflammatory and neuropathic pain.

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18 results for "GPR55" in Products

18 results for "GPR55" in Products

GPR55 Products

Members of the G protein-coupled receptor (GPCR) family, such as GPR55, play important roles in signal transduction from the external environment to the inside of the cell. GPR55 is a receptor for L-alpha-lysophosphatidylinositol (LPI). LPI induces Ca2+ release from intracellular stores via the heterotrimeric G protein GNA13 and RHOA. GPR55 is expressed in the caudate nucleus and putamen, but not detected in the hippocampus, thalamus, pons cerebellum, frontal cortex of the brain or in the liver. It is expressed in osteoclasts and osteoblasts. GPR55 may play a role in bone physiology by regulating osteoclast number and function. GPR55 may also be involved in hyperalgesia associated with inflammatory and neuropathic pain.

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Applications: IHC, WB, ICC/IF
Reactivity: Human, Canine, Equine
Applications: IHC
Reactivity: Human
Applications: WB, ELISA, ICC/IF
Reactivity: Mouse, Rat
Applications: WB
Reactivity: Mouse, Rat
Applications: WB
Reactivity: Human
Applications: WB

Potent CB1 antagonist; also GPR55 agonist

Endogenous and non-selective CB agonist

Selective GPR55 agonist. FAAH and PAA substrate

Natural cannabinoid; GPR55 antagonist, weak CB1 antagonist, CB2 inverse agonist and AMT inhibitor

Endogenous and non-selective CB agonist; potent GPR55 agonist

Potent GPR55 agonist

Selective GPR55 antagonist

Potent, selective GPR55 antagonist

Selective GPR55 agonist; also promotes NSC proliferation and differentiation

Lipid mediator, anorexic actions; also GPR55 and PPARα agonist

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