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GRAP2 Products

GRAP2 (GRB2 related adaptor protein 2), a divergent member of the GRB2/Sem5/Drk family, is an adaptor protein involved in leukocyte-specific protein-tyrosine kinase signaing. GRAP2 shares similar structural organization as GRB2 and GRAP with a central SH2 domain flanked by two SH3 domains. However, unlike GRB2 and GRAP, the SH2 domain and the C-terminal SH3 domain of GRAP2 contains a unique 120-amino acid glutamine/proline rich sequence. In T lymphocytes, GRAP2 interacts with LAT and SLP-76 to regulate NF-AT (nuclear factor of activated T cells) and form a signaling complex with HPK1 to mediate the JNK signaling pathway. GRAP2 also interacts with M-CSF R and the activated T cell co-stimulatory receptor CD28.

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45 results for "GRAP2" in Products

45 results for "GRAP2" in Products

GRAP2 Products

GRAP2 (GRB2 related adaptor protein 2), a divergent member of the GRB2/Sem5/Drk family, is an adaptor protein involved in leukocyte-specific protein-tyrosine kinase signaing. GRAP2 shares similar structural organization as GRB2 and GRAP with a central SH2 domain flanked by two SH3 domains. However, unlike GRB2 and GRAP, the SH2 domain and the C-terminal SH3 domain of GRAP2 contains a unique 120-amino acid glutamine/proline rich sequence. In T lymphocytes, GRAP2 interacts with LAT and SLP-76 to regulate NF-AT (nuclear factor of activated T cells) and form a signaling complex with HPK1 to mediate the JNK signaling pathway. GRAP2 also interacts with M-CSF R and the activated T cell co-stimulatory receptor CD28.

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Applications: IHC, WB, Flow
Reactivity: Human, Mouse, Rat
Applications: WB
Reactivity: Human, Mouse
Applications: WB
Reactivity: Human
Applications: IHC, WB, ELISA, IP
Reactivity: Human
Applications: IHC, WB
Reactivity: Human
Applications: WB, ELISA
Reactivity: Human
Applications: PAGE
Applications: WB
Applications: AC
Applications: IHC, WB, Flow, CyTOF-ready
Reactivity: Human, Mouse, Rat
Applications: IHC, WB, Flow, CyTOF-ready
Reactivity: Human, Mouse, Rat
Applications: IHC, WB, Flow, CyTOF-ready
Reactivity: Human, Mouse, Rat
Applications: IHC, WB, Flow, CyTOF-ready
Reactivity: Human, Mouse, Rat
Applications: IHC, WB, Flow, CyTOF-ready
Reactivity: Human, Mouse, Rat
Applications: IHC, WB, Flow
Reactivity: Human, Mouse, Rat
Applications: IHC, WB, Flow
Reactivity: Human, Mouse, Rat
Applications: IHC, WB, Flow
Reactivity: Human, Mouse, Rat
Applications: IHC, WB, Flow
Reactivity: Human, Mouse, Rat
Applications: IHC, WB, Flow
Reactivity: Human, Mouse, Rat
Applications: IHC, WB, Flow
Reactivity: Human, Mouse, Rat
Applications: IHC, WB, Flow
Reactivity: Human, Mouse, Rat
Applications: IHC, WB, Flow
Reactivity: Human, Mouse, Rat
Applications: IHC, WB, Flow
Reactivity: Human, Mouse, Rat
Applications: IHC, WB, Flow
Reactivity: Human, Mouse, Rat
Applications: IHC, WB, Flow
Reactivity: Human, Mouse, Rat
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