Histamine H4 Receptor Antagonists: Small Molecules and Peptides
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by a family of histamine receptors, which are a subset of the G protein-coupled receptor superfamily. Histamine H4 R is a histamine receptor that is predominantly expressed in hematopoietic cells. Histamine H4 R is thought to play a role in inflammation and allergy reponses.
3 results for "Histamine H4 Receptor Antagonists Small Molecules and Peptides" in Products
3 results for "Histamine H4 Receptor Antagonists Small Molecules and Peptides" in Products
Histamine H4 Receptor Antagonists: Small Molecules and Peptides
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by a family of histamine receptors, which are a subset of the G protein-coupled receptor superfamily. Histamine H4 R is a histamine receptor that is predominantly expressed in hematopoietic cells. Histamine H4 R is thought to play a role in inflammation and allergy reponses.
High affinity and selective histamine H4 antagonist; orally bioavailable
| Chemical Name: | 4-[(3R)-3-Amino-1-pyrrolidinyl]-6-(1-methylethyl)-2-pyridinamine dihydrochloride |
| Purity: | ≥98% (HPLC) |
Selective H4 antagonist
| Chemical Name: | 1-[(5-Chloro-1H-indol-2-yl)carbonyl]-4-methylpiperazine |
| Purity: | ≥98% (HPLC) |
Selective H4 antagonist; orally active
| Alternate Names: | VUF 6002 |
| Chemical Name: | 1-[(5-Chloro-1H-benzimidazol-2-yl)carbonyl]-4-methylpiperazine maleate |
| Purity: | ≥99% (HPLC) |
