Histone H2AX Products
Histone H2AX is one of a number of core histone proteins. In the cellular response to genotoxic insults, ATM and related protein kinases phosphorylate the carboxyl-terminal tail of the H2AX protein (gamma-H2AX). gamma-H2AX marks the site of damage and provides a nucleation site for the formation of damage response and repair complexes. BRCA1 carboxyl terminal (BRCT) domain-containing proteins are recruited to gamma-H2AX to create a protein scaffold for further assembly of signaling complexes.
Products:
2 results for "Histone H2AX" in Products
2 results for "Histone H2AX" in Products
Histone H2AX Products
Histone H2AX is one of a number of core histone proteins. In the cellular response to genotoxic insults, ATM and related protein kinases phosphorylate the carboxyl-terminal tail of the H2AX protein (gamma-H2AX). gamma-H2AX marks the site of damage and provides a nucleation site for the formation of damage response and repair complexes. BRCA1 carboxyl terminal (BRCT) domain-containing proteins are recruited to gamma-H2AX to create a protein scaffold for further assembly of signaling complexes.
Products:
Reactivity: | Human, Mouse, Bovine, Rabbit |
Details: | Mouse IgG1 kappa Monoclonal Clone #3F2 |
Applications: | IHC, WB, ICC/IF, ELISA, Flow, +2 More |
Reactivity: | Human, Mouse, Rat, Canine, Bovine, +7 More |
Details: | Mouse IgG1 kappa Monoclonal Clone #9F3 |
Applications: | WB, ICC/IF |