IGFBP-3 Products
IGFBP-3 (Insulin-like growth factor binding protein-3) modulates the biological activity of IGF. It circulates in a ternary complex with IGF and the acid-labile subunit (ALS). Proteolysis of IGFBP-3 by tissue plasminogen activator (tPA), a disintegrin and metalloproteases (ADAMs), and prostate specific antigen (PSA) contributes to IGFBP-3 degradation or a reduction in its affinity for IGF. The majority of soluble IGFBP-3 found in circulation is secreted from hepatic non-parenchymal cells. IGFBP-3 potentiates EGF-EGFR-mediated cell growth, modulates adipogenesis, and regulates TGF-beta signaling, DNA damage, apoptosis, autophagy, and gene transcription.
30 results for "IGFBP-3" in Products
30 results for "IGFBP-3" in Products
IGFBP-3 Products
IGFBP-3 (Insulin-like growth factor binding protein-3) modulates the biological activity of IGF. It circulates in a ternary complex with IGF and the acid-labile subunit (ALS). Proteolysis of IGFBP-3 by tissue plasminogen activator (tPA), a disintegrin and metalloproteases (ADAMs), and prostate specific antigen (PSA) contributes to IGFBP-3 degradation or a reduction in its affinity for IGF. The majority of soluble IGFBP-3 found in circulation is secreted from hepatic non-parenchymal cells. IGFBP-3 potentiates EGF-EGFR-mediated cell growth, modulates adipogenesis, and regulates TGF-beta signaling, DNA damage, apoptosis, autophagy, and gene transcription.
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #138202 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rat IgG2 Monoclonal Clone #RM0096-11B16 |
| Applications: | WB |
![Western Blot: IGFBP-3 Antibody (RM0096-11B16)Azide and BSA Free [NBP1-22452]](https://resources.bio-techne.com/images/products/IGFBP-3-Antibody-RM0096-11B16-Western-Blot-NBP1-22452-img0001.jpg "Western Blot: IGFBP-3 Antibody (RM0096-11B16)Azide and BSA Free [NBP1-22452]")
| Reactivity: | Mouse |
| Details: | Rat IgG2 Monoclonal Clone #RM0096-11B16 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rat IgG2 Monoclonal Clone #RM0096-11B16 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rat IgG2 Monoclonal Clone #RM0096-11B16 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rat IgG2 Monoclonal Clone #RM0096-11B16 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rat IgG2 Monoclonal Clone #RM0096-11B16 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rat IgG2 Monoclonal Clone #RM0096-11B16 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rat IgG2 Monoclonal Clone #RM0096-11B16 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rat IgG2 Monoclonal Clone #RM0096-11B16 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rat IgG2 Monoclonal Clone #RM0096-11B16 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rat IgG2 Monoclonal Clone #RM0096-11B16 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rat IgG2 Monoclonal Clone #RM0096-11B16 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rat IgG2 Monoclonal Clone #RM0096-11B16 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rat IgG2 Monoclonal Clone #RM0096-11B16 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rat IgG2 Monoclonal Clone #RM0096-11B16 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rat IgG2 Monoclonal Clone #RM0096-11B16 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rat IgG2 Monoclonal Clone #RM0096-11B16 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rat IgG2 Monoclonal Clone #RM0096-11B16 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rat IgG2 Monoclonal Clone #RM0096-11B16 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rat IgG2 Monoclonal Clone #RM0096-11B16 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rat IgG2 Monoclonal Clone #RM0096-11B16 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rat IgG2 Monoclonal Clone #RM0096-11B16 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rat IgG2 Monoclonal Clone #RM0096-11B16 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rat IgG2 Monoclonal Clone #RM0096-11B16 |
| Applications: | WB |