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IkB-alpha: Proteins and Enzymes

The inhibitory IkB proteins (alpha, beta, epsilon) complex with and sequester NFkB family members in the cytoplasm, rendering these transcription factors inactive. When phosphorylated by an active IkB kinase (IKK) complex, IkB proteins are degraded by proteasomes, resulting in the release and nuclear translocation of active NFkB.

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3 results for "IkB-alpha Proteins and Enzymes" in Products

3 results for "IkB-alpha Proteins and Enzymes" in Products

IkB-alpha: Proteins and Enzymes

The inhibitory IkB proteins (alpha, beta, epsilon) complex with and sequester NFkB family members in the cytoplasm, rendering these transcription factors inactive. When phosphorylated by an active IkB kinase (IKK) complex, IkB proteins are degraded by proteasomes, resulting in the release and nuclear translocation of active NFkB.

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