IL-10: Proteins and Enzymes
IL-10 (Interleukin-10) functions as an anti-inflammatory cytokine by inhibiting the expansion and activation of Th1 cells and Th17 cells and by promoting the development of M2 macrophages and regulatory T cells (Treg). Within a tumor microrenvironment, however, IL-10 can inhibit the expansion of both Treg and myeloid-derived suppressor cells (MDSC). IL-10 exerts protective effects including limiting tissue damage in arthritic inflammation and promoting muscle regeneration after injury, but it also contributes to the persistence of viral infections. IL-10 signals through a receptor complex composed of IL-10 R alpha and IL-10 R beta. IL-10 R beta additionally associates with IL-20 R alpha, IL-22 R alpha 1, or IL-28 R alpha to form the receptor complexes for IL-22, IL-26, IL-28, and IL-29.
25 results for "IL-10 Proteins and Enzymes" in Products
25 results for "IL-10 Proteins and Enzymes" in Products
IL-10: Proteins and Enzymes
IL-10 (Interleukin-10) functions as an anti-inflammatory cytokine by inhibiting the expansion and activation of Th1 cells and Th17 cells and by promoting the development of M2 macrophages and regulatory T cells (Treg). Within a tumor microrenvironment, however, IL-10 can inhibit the expansion of both Treg and myeloid-derived suppressor cells (MDSC). IL-10 exerts protective effects including limiting tissue damage in arthritic inflammation and promoting muscle regeneration after injury, but it also contributes to the persistence of viral infections. IL-10 signals through a receptor complex composed of IL-10 R alpha and IL-10 R beta. IL-10 R beta additionally associates with IL-20 R alpha, IL-22 R alpha 1, or IL-28 R alpha to form the receptor complexes for IL-22, IL-26, IL-28, and IL-29.
Analyzed by SEC-MALS.
Source: | E. coli |
Accession #: | P22301.1 |
Applications: | BA |
Animal Free
Source: | E. coli |
Accession #: | P22301.1 |
Applications: | BA |
Source: | E. coli |
Accession #: | NP_034678 |
Applications: | BA |
Source: | E. coli |
Accession #: | P29456.1 |
Applications: | BA |
Analyzed by SEC-MALS
Source: | Sf 21 (baculovirus) |
Accession #: | P22301 |
Applications: | BA |
Source: | E. coli |
Accession #: | AAF63437 |
Applications: | BA |
Source: | E. coli |
Accession #: | XP_855560 |
Applications: | BA |
Source: | E. coli |
Accession #: | P03180 |
Applications: | BA |
Source: | E. coli |
Accession #: | Q29055 |
Applications: | BA |
Intended for preclinical researchers who may transition to GMP IL-10 for their clinical work
Source: | E. coli |
Accession #: | P22301.1 |
Applications: | BA |
Source: | E. coli |
Accession #: | NP_034678 |
Applications: | BA |
Source: | E. coli |
Accession #: | P29456 |
Applications: | BA |
Source: | HEK293 |
Accession #: | P18893.2 |
Applications: | BA |
Source: | HEK293 |
Accession #: | P22301.1 |
Applications: | BA |
Source: | E. coli |
Accession #: | AAK94013 |
Applications: | BA |
Source: | E. coli |
Accession #: | P55029.2 |
Applications: | BA |
Source: | E. coli |
Accession #: | Q28374 |
Applications: | BA |
Applications: | Bioactivity, PAGE |
Source: | Sf 21 (stably transfected) |
Accession #: | P22301 |
Applications: | BA |
Applications: | WB, ELISA |
Applications: | ELISA |
Applications: | AC |
Applications: | Bioactivity, PAGE |
Applications: | Bioactivity, PAGE |
Applications: | WB, Bioactivity |