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IL-12 p70: Simple Plex

IL-12 (Interleukin-12) is a secreted heterodimeric cytokine that contains disulfide-linked p35 and p40 subunits. The p40 subunit is also a subunit of the heterodimeric IL-23. IL-12 is produced by macrophages, dendritic cells, monocytes, Langerhans cells, neutrophils, keratinocytes, microglia, and non-germinal center B cells. It acts through a receptor complex that contains the ligand binding IL-12 R alpha 1 and the signal transducing IL-12 R alpha 2. IL-12 can enhance cytotoxic activity and induce Interferon-gamma production in NK cells, T cells, and dendritic epidermal T cells. In conjunction with IL-23 and IL-27, IL-12 promotes the development of a Th1 immune response.

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6 results for "IL-12 p70 Simple Plex" in Products

6 results for "IL-12 p70 Simple Plex" in Products

IL-12 p70: Simple Plex

IL-12 (Interleukin-12) is a secreted heterodimeric cytokine that contains disulfide-linked p35 and p40 subunits. The p40 subunit is also a subunit of the heterodimeric IL-23. IL-12 is produced by macrophages, dendritic cells, monocytes, Langerhans cells, neutrophils, keratinocytes, microglia, and non-germinal center B cells. It acts through a receptor complex that contains the ligand binding IL-12 R alpha 1 and the signal transducing IL-12 R alpha 2. IL-12 can enhance cytotoxic activity and induce Interferon-gamma production in NK cells, T cells, and dendritic epidermal T cells. In conjunction with IL-23 and IL-27, IL-12 promotes the development of a Th1 immune response.

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Applications: Simple Plex

Cartridges below are for plasma/serum (PS-000498) cartridges. Stocked cartridges are indicated with ST01 and available to ship in 3-4 days. Simple Plex Human IL-12 p70 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash

Applications: Ctrl, Simple Plex

Control for use with Human IL-12 p70 Simple Plex Cartridge Kit

Applications: Simple Plex

Simple Plex Mouse IL-12 p70 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD09, and wash buffer.

Applications: Simple Plex

Control for use with Mouse IL-12 p70 Simple Plex Assay Cartridge Kit

Applications: Simple Plex

Simple Plex 32x8 panel containing IL-1b, IL-12 p70, IL-10 2nd Gen, IL-4 2nd Gen, IL-2, IFNg 3rd Gen, TNF-a 2nd Gen, and IL-6 3rd Gen with sample diluent SD13. Part # starting with ST01 ships in 3-5 days. Sample type indicated with PS (Plasma/Serum).

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