IL-1ra/IL-1F3 Products
IL-1ra (IL-1 receptor antagonist) is a widely expressed acute phase protein that serves to dampen inflammation. IL-1ra binds to both IL-1 RI and IL-1 RII. It competitively inhibits IL-1 (alpha or beta) binding to IL-1 RI and does not trigger recruitment of the accessory molecule IL-1 R AcP or activation of IL-1 RI signaling. IL-1ra blocks the proinflammatory actions of IL-1 including Prostaglandin E2 and IL-6 release from endothelial cells, fever generation, thrombocytosis, the production of hepatic acute phase proteins, and neutrophil expansion and infiltration.
9 results for "IL-1ra/IL-1F3" in Products
9 results for "IL-1ra/IL-1F3" in Products
IL-1ra/IL-1F3 Products
IL-1ra (IL-1 receptor antagonist) is a widely expressed acute phase protein that serves to dampen inflammation. IL-1ra binds to both IL-1 RI and IL-1 RII. It competitively inhibits IL-1 (alpha or beta) binding to IL-1 RI and does not trigger recruitment of the accessory molecule IL-1 R AcP or activation of IL-1 RI signaling. IL-1ra blocks the proinflammatory actions of IL-1 including Prostaglandin E2 and IL-6 release from endothelial cells, fever generation, thrombocytosis, the production of hepatic acute phase proteins, and neutrophil expansion and infiltration.
| Sensitivity: | 13 pg/mL |
| Applications: | ELISA |
| Assay Range: | 31.2 - 2,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma) |
| Source: | E. coli |
| Accession #: | Q542W1 |
| Applications: | BA |
| Assay Range: | 156 - 10,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Neut |
| Reactivity: | Mouse |
| Details: | Rat IgG1 Monoclonal Clone #694204 |
| Applications: | WB |
| Reactivity: | Human, Mouse |
| Details: | Rat IgG2a Monoclonal Clone #40007 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #SR1317 |
| Applications: | IHC, WB, ICC/IF, Flow, IP |
| Applications: | Bioactivity, PAGE |
![SDS-PAGE: Recombinant Mouse IL-1ra/IL-1F3/IL1RN Protein [NBP2-35105]](https://resources.bio-techne.com/images/products/Mouse-IL-1ra-IL-1F3-IL1RN-Protein-SDS-Page-NBP2-35105-img0001.jpg "SDS-PAGE: Recombinant Mouse IL-1ra/IL-1F3/IL1RN Protein [NBP2-35105]")