IL-27: Lysates
IL-27 is a heterodimeric cytokine that is composed of EBI3 (which is related to the p40 subunit of IL-12 and IL-23) and p28 (which is related to the p35 chain of IL-12). IL-27 is expressed by monocytes, endothelial cells, and dendritic cells. It signals through a receptor complex composed of IL-27 R alpha/WSX-1/TCCR and gp130. IL-27 induces IL-12 receptor expression on naïve CD4+ T cells, sensitizing them to subsequent IL-12-induced Th1 development. It also functions as an anti-inflammatory cytokine by limiting T and NKT cell activity.
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1 result for "IL-27 Lysates" in Products
1 result for "IL-27 Lysates" in Products
IL-27: Lysates
IL-27 is a heterodimeric cytokine that is composed of EBI3 (which is related to the p40 subunit of IL-12 and IL-23) and p28 (which is related to the p35 chain of IL-12). IL-27 is expressed by monocytes, endothelial cells, and dendritic cells. It signals through a receptor complex composed of IL-27 R alpha/WSX-1/TCCR and gp130. IL-27 induces IL-12 receptor expression on naïve CD4+ T cells, sensitizing them to subsequent IL-12-induced Th1 development. It also functions as an anti-inflammatory cytokine by limiting T and NKT cell activity.
Products:
| Applications: | WB |
![Western Blot: IL-27 Overexpression Lysate [NBL1-11947]](https://resources.bio-techne.com/images/products/IL27-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-11947-img0002.jpg "Western Blot: IL-27 Overexpression Lysate [NBL1-11947]")