IRF2 Products
IRF2 functions as a regulator of type I interferons influencing cellular proliferation and immune response through transcriptional regulation. IRF2 competitively inhibits IRF1 gene activation, as well as, stimulating transcription on its own. Over-expression of IRF2 in NIH3T3 cells leads to transformation, whereas, loss of IRF2 expression in knock out mice leads to a variety of abnormalities including loss of NK cells due to increased apoptosis.
4 results for "IRF2" in Products
4 results for "IRF2" in Products
IRF2 Products
IRF2 functions as a regulator of type I interferons influencing cellular proliferation and immune response through transcriptional regulation. IRF2 competitively inhibits IRF1 gene activation, as well as, stimulating transcription on its own. Over-expression of IRF2 in NIH3T3 cells leads to transformation, whereas, loss of IRF2 expression in knock out mice leads to a variety of abnormalities including loss of NK cells due to increased apoptosis.
Reactivity: | Human, Mouse |
Details: | Sheep IgG Polyclonal |
Applications: | WB |
Reactivity: | Human |
Details: | Goat IgG Polyclonal |
Applications: | WB, Simple Western |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, ICC/IF |
Reactivity: | Human, Mouse |
Details: | Goat IgG Polyclonal |
Applications: | WB, ELISA |