JNK1 Products
Members of the MAPK family, the c-Jun N-terminal kinases (JNKs) are activated by environmental stresses and inflammatory cytokines. Ten JNK isoforms are created by alternative splicing of mRNA transcripts derived from three genes: JNK1, JNK2, and JNK3. All JNKs are activated by dual phosphorylation; at T183/Y185 for JNK1 and 2, and T221/Y223 for JNK3. Activated JNKs translocate to the nucleus where they regulate the activity of several transcription factors; including the c-Jun component of AP-1 and ATF-2.
30 results for "JNK1" in Products
30 results for "JNK1" in Products
JNK1 Products
Members of the MAPK family, the c-Jun N-terminal kinases (JNKs) are activated by environmental stresses and inflammatory cytokines. Ten JNK isoforms are created by alternative splicing of mRNA transcripts derived from three genes: JNK1, JNK2, and JNK3. All JNKs are activated by dual phosphorylation; at T183/Y185 for JNK1 and 2, and T221/Y223 for JNK3. Activated JNKs translocate to the nucleus where they regulate the activity of several transcription factors; including the c-Jun component of AP-1 and ATF-2.
Reactivity: | Human, Mouse, Rat |
Details: | Mouse IgG1 Monoclonal Clone #228601 |
Applications: | WB, ICC |
Reactivity: | Human, Mouse, Rat |
Details: | Mouse IgG2a Monoclonal Clone #252323 |
Applications: | WB, Simple Western, ICC |
Reactivity: | Human, Mouse, Rat |
Details: | Mouse IgG1 Monoclonal Clone #228611 |
Applications: | WB |
Reactivity: | Rat (Negative), Mouse (Negative), C. elegans, Human (Negative), Nematode - Caenorhabditis elegans, +1 More |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ELISA |
Reactivity: | Human, Mouse, Rat |
Details: | Mouse IgG2A Monoclonal Clone #OTI4E3 |
Applications: | IHC, WB, ICC/IF |
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB |
Reactivity: | Human, Mouse, Rat |
Details: | Mouse IgG1 Monoclonal Clone #1E5 |
Applications: | WB, ELISA, ICC/IF, Flow, CyTOF-ready |
Reactivity: | Human |
Details: | Mouse IgG2a Kappa Monoclonal Clone #2F11 |
Applications: | WB, ELISA, ICC/IF, Func, KD |
Source: | Sf 9 (baculovirus) |
Accession #: | NP_002741 |
Applications: | BA |
Recombinant Monoclonal Antibody
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Monoclonal Clone #8Q7S4 |
Applications: | IHC, WB, ICC/IF |
Applications: | WB |
Applications: | WB |
Applications: | WB |
Reactivity: | Human, Mouse, Rat |
Details: | Mouse IgG2A Monoclonal Clone #OTI4E3 |
Applications: | IHC, WB, ICC/IF |
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, Simple Western, IHC |
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, Simple Western, IHC |
Recombinant Monoclonal Antibody.
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Monoclonal Clone #1006A |
Applications: | WB, Simple Western, ICC |
Selective JNK inhibitor
Chemical Name: | Anthra[1-9-cd]pyrazol-6(2H)-one |
Purity: | ≥98% (HPLC) |
Inhibitor of JNK signaling
Chemical Name: | (9S,10R,12R)-5-16-Bis[(ethylthio)methyl]-2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid methyl ester |
Purity: | ≥97% (HPLC) |
Reactivity: | Human, Mouse, Rat |
Details: | Mouse IgG2a Monoclonal Clone #252355 |
Applications: | WB, Simple Western |
Assay Range: | 156 - 10,000 pg/mL |
Applications: | ELISA |
Selective JNK inhibitor
Chemical Name: | N-(4-Amino-5-cyano-6-ethoxy-2-pyridinyl)-2,5-dimethoxybenzeneacetamide |
Purity: | ≥98% (HPLC) |
TCS JNK 6o synthesized to Ancillary Material Grade
Chemical Name: | N-(4-Amino-5-cyano-6-ethoxy-2-pyridinyl)-2,5-dimethoxybenzeneacetamide |
Purity: | ≥98% |
Highly potent and selective JNK3 inhibitor
Chemical Name: | 3-[4-[[[(3-Methylphenyl)amino]carbonyl]amino]-1H-pyrazol-1-yl]-N-(3,4,5-trimethoxyphenyl)benzamide |
Purity: | ≥97% (HPLC) |
High affinity JNK inhibitor; also inhibits HCMV replication
Chemical Name: | 3-[3-[2-(1-Piperidinyl)ethoxy]phenyl]-5-(1H-1,2,4-triazol-5-yl)-1H-indazole dihydrochloride |
Purity: | ≥98% (HPLC) |