LAT Products
LAT (Linker for Activation of T cells) is a type III transmembrane lipid raft protein that serves as a scaffold for signaling molecules. Upon T-cell antigen receptor activation, LAT is multiply phosphorylated by ZAP-70/Syk protein tyrosine kinases, creating docking sites for SH2 domain-containing proteins. For example, phospholipase C-gamma docks at Y161, which is pY132 in the short form. Mutation of this site results in a Th2 autoimmune lymphoproliferative disorder in mice.
79 results for "LAT" in Products
79 results for "LAT" in Products
LAT Products
LAT (Linker for Activation of T cells) is a type III transmembrane lipid raft protein that serves as a scaffold for signaling molecules. Upon T-cell antigen receptor activation, LAT is multiply phosphorylated by ZAP-70/Syk protein tyrosine kinases, creating docking sites for SH2 domain-containing proteins. For example, phospholipase C-gamma docks at Y161, which is pY132 in the short form. Mutation of this site results in a Th2 autoimmune lymphoproliferative disorder in mice.
Reactivity: | Human |
Details: | Mouse IgG1 kappa Monoclonal Clone #LAT.10-17 |
Applications: | IHC, WB, Flow, IP |
Reactivity: | Human |
Details: | Mouse IgG1 kappa Monoclonal Clone #LAT.10-17 |
Applications: | IHC, WB, Flow, IP |
Reactivity: | Human |
Details: | Mouse IgG1 kappa Monoclonal Clone #LAT.10-17 |
Applications: | IHC, WB, Flow, IP |
Reactivity: | Human |
Details: | Mouse IgG1 kappa Monoclonal Clone #LAT.10-17 |
Applications: | IHC, WB, Flow, IP |
Reactivity: | Human |
Details: | Mouse IgG1 kappa Monoclonal Clone #LAT.10-17 |
Applications: | IHC, WB, Flow, IP |
Reactivity: | Human |
Details: | Mouse IgG1 kappa Monoclonal Clone #LAT.10-17 |
Applications: | IHC, WB, Flow, IP |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #661002 |
Applications: | WB |
Recombinant Monoclonal Antibody
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Monoclonal Clone #SR1644 |
Applications: | IHC, WB, ICC/IF, IP |
Reactivity: | Human, Mouse, Primate |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #627945 |
Applications: | WB |
Reactivity: | Human |
Details: | Sheep IgG Polyclonal |
Applications: | WB |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ICC/IF |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Rabbit IgG Monoclonal Clone #2E4 |
Applications: | IHC, WB, ELISA, ICC/IF, IP |
Reactivity: | Human, Mouse |
Details: | Rabbit IgG Polyclonal |
Applications: | WB |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Rabbit IgG Monoclonal Clone #SR1593 |
Applications: | IHC, WB |
Reactivity: | Human, Mouse, Rat |
Details: | Goat IgG Polyclonal |
Applications: | WB, ELISA |
Applications: | WB |
Applications: | ELISA |
Applications: | ELISA |
Applications: | PAGE |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, IP |
Applications: | AC |
Reactivity: | Human |
Details: | Mouse IgG2B Monoclonal Clone #661002 |
Applications: | WB |
Reactivity: | Human |
Details: | Mouse IgG2B Monoclonal Clone #661002 |
Applications: | WB |
Reactivity: | Human |
Details: | Mouse IgG2B Monoclonal Clone #661002 |
Applications: | WB |