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LILRB1/CD85j/ILT2: Proteins and Enzymes

LILRB1, also known as CD85j and ILT2, is a transmembrane immunoregulatory protein that is expressed on the surface of B cells and monocytes, as well as subsets of NK cells, memory/effector CD8+ T cells, gamma/delta T cells, and monocyte-derived dendritic cells. LILRB1 binds to MHC-I as well as non-classical MHC-I molecules (e.g. HLA-F, HLA-G, and HC-B27), the MHC-I mimetic UL18 encoded by cytomegalovirus, and Angiopoietin-like 7.

Ligation of LILRB1 inhibits the antigen-induced proliferation and activation of CD8+ T cells, CD4+ T cells, NK cells, and gamma/delta T cells. On dendritic cells, ligation inhibits the production of IL-10, IL-12p70, and TGF-beta and protects from Fas-mediated apoptosis.

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5 results for "LILRB1/CD85j/ILT2 Proteins and Enzymes" in Products

LILRB1/CD85j/ILT2: Proteins and Enzymes

LILRB1, also known as CD85j and ILT2, is a transmembrane immunoregulatory protein that is expressed on the surface of B cells and monocytes, as well as subsets of NK cells, memory/effector CD8+ T cells, gamma/delta T cells, and monocyte-derived dendritic cells. LILRB1 binds to MHC-I as well as non-classical MHC-I molecules (e.g. HLA-F, HLA-G, and HC-B27), the MHC-I mimetic UL18 encoded by cytomegalovirus, and Angiopoietin-like 7.

Ligation of LILRB1 inhibits the antigen-induced proliferation and activation of CD8+ T cells, CD4+ T cells, NK cells, and gamma/delta T cells. On dendritic cells, ligation inhibits the production of IL-10, IL-12p70, and TGF-beta and protects from Fas-mediated apoptosis.

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Applications: BA

Biotinylated

Applications: BA

Biotinylated

Applications: BA

Biotinylated

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