MCT1/SLC16A1 Products
MCT1/SLC16A1 is a proton-linked monocarboxylate transporter that catalyzes the movement of many monocarboxylates, such as lactate and pyruvate, across the plasma membrane. Mutations in this gene are associated with erythrocyte lactate transporter defect. SLC16A1 may be a potential therapeutic target combining antimetabolic and anti-angiogenic activities. SLC16A1 blockers could act as HIF-1 inhibitors leading to anti-angiogenic effects.
38 results for "MCT1/SLC16A1" in Products
38 results for "MCT1/SLC16A1" in Products
MCT1/SLC16A1 Products
MCT1/SLC16A1 is a proton-linked monocarboxylate transporter that catalyzes the movement of many monocarboxylates, such as lactate and pyruvate, across the plasma membrane. Mutations in this gene are associated with erythrocyte lactate transporter defect. SLC16A1 may be a potential therapeutic target combining antimetabolic and anti-angiogenic activities. SLC16A1 blockers could act as HIF-1 inhibitors leading to anti-angiogenic effects.
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, KD |
![Knockdown Validated: MCT1/SLC16A1 Antibody - BSA Free [NBP1-59656]](https://resources.bio-techne.com/images/products/MCT1-SLC16A1-Antibody-Knockdown-Validated-NBP1-59656-img0007.jpg "Western Blot: MCT1/SLC16A1 Antibody - BSA Free [NBP1-59656]")
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG Polyclonal |
| Applications: | WB, ICC/IF |
![Western Blot: MCT1/SLC16A1 Antibody [H00006566-B01P]](https://resources.bio-techne.com/images/products/MCT1-SLC16A1-Antibody-Western-Blot-H00006566-B01P-img0004.jpg "Western Blot: MCT1/SLC16A1 Antibody [H00006566-B01P]")
Recombinant monoclonal antibody expressed in HEK293F cells
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #9D12 |
| Applications: | IHC, WB, ELISA |
![Western Blot: MCT1/SLC16A1 Antibody (9D12) [NBP3-15184]](https://resources.bio-techne.com/images/products/MCT1-SLC16A1-Antibody-9D12-Western-Blot-NBP3-15184-img0003.jpg "Western Blot: MCT1/SLC16A1 Antibody (9D12) [NBP3-15184]")
| Applications: | WB, ELISA, MA, AP, PAGE |
![SDS-PAGE: Recombinant Human MCT1/SLC16A1 GST (N-Term) Protein [H00006566-P01]](https://resources.bio-techne.com/images/products/qc_test-H00006566-P01-1.jpg "SDS-PAGE: Recombinant Human MCT1/SLC16A1 GST (N-Term) Protein [H00006566-P01]")
| Applications: | AC |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, KD |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, KD |
MCT1 inhibitor; also inhibits hexokinase II
| Chemical Name: | 3-Bromo-2-oxopropanoic acid |
MCT inhibitor; decreases glycoloysis
| Chemical Name: | 2-Cyano-3-(4-hydroxyphenyl)-2-propenoic acid |
| Purity: | ≥98% (HPLC) |
MCT1 and MCT2 inhibitor; inhibits glycolysis in cancer cells
| Chemical Name: | 6-[(3,5-Dimethyl-1H-pyrazol-4-yl)methyl]-5-[[(4S)-4-hydroxy-2-isoxazolidinyl]carbonyl]-3-methyl-1-(2-methylpropyl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione |
| Purity: | ≥98% (HPLC) |
Potent MCT1 inhibitor
| Chemical Name: | 2,6-Dihydro-7-[(3-hydroxypropyl)thio]-2-methyl-4-(2-methylpropyl)-6-(1-naphthalenylmethyl)-1H-pyrrolo[3,4-d]pyridazin-1one |
| Purity: | ≥98% (HPLC) |
MCT1 inhibitor
| Chemical Name: | 5-[[(3R)-3-Hydroxy-1-pyrrolidinyl]carbonyl]-3-methyl-1-(2-methylpropyl)-6-(4-quinolinylmethyl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione |
| Purity: | ≥98% (HPLC) |
MCT inhibitor; also inhibits mitochondrial pyruvate carrier
| Chemical Name: | 2-Cyano-3-(1-phenyl-1H-indol-3-yl)-2-propenoic acid |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, KD |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, KD |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, KD |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, KD |
![MCT1/SLC16A1 Antibody [Alexa Fluor® 647]](https://resources.bio-techne.com/images/products/nbp1-59656af647_rabbit-polyclonal-mct1-slc16a1-antibody-alexa-fluor-647-immunocytochemistry-immunofluorescence-279202413442..jpg "MCT1/SLC16A1 in HepG2 Human Cell Line.")
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, KD |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, KD |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, KD |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, KD |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, KD |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, KD |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, KD |