PDGF R beta: ELISA Kits
PDGF R beta is a transmembrane receptor tyrosine kinase (RTK) that primarily binds to the PDGF-BB isoform of the growth factor. Ligand binding induces receptor homodimerization or heterodimerization with PDGF R alpha followed by autophosphorylation and signal transduction. PDGF receptor signaling is attenuated by SHP-2 phosphatase activity and by receptor endocytosis and lysosomal degradation. The expression of the alpha and beta receptors is independently regulated in various cell types. A soluble splice variant of PDGF R beta binds PDGF with high affinity and functions as a potent PDGF antagonist.
Products:
5 results for "PDGF R beta ELISA Kits" in Products
5 results for "PDGF R beta ELISA Kits" in Products
PDGF R beta: ELISA Kits
PDGF R beta is a transmembrane receptor tyrosine kinase (RTK) that primarily binds to the PDGF-BB isoform of the growth factor. Ligand binding induces receptor homodimerization or heterodimerization with PDGF R alpha followed by autophosphorylation and signal transduction. PDGF receptor signaling is attenuated by SHP-2 phosphatase activity and by receptor endocytosis and lysosomal degradation. The expression of the alpha and beta receptors is independently regulated in various cell types. A soluble splice variant of PDGF R beta binds PDGF with high affinity and functions as a potent PDGF antagonist.
Products:
| Applications: | ELISA |
| Assay Range: | 15.6 - 1,000 pg/mL |
| Applications: | ELISA |
| Assay Range: | 125 - 8,000 pg/mL |
| Applications: | ELISA |
| Assay Range: | 250 - 16,000 pg/mL |
| Applications: | ELISA |
| Applications: | ELISA |
