PLA2G7/PAF-AH/Lp-PLA2 Products
Secretory phopholipase A2 (PLA2) enzymes cleave an acyl ester bond in the sn-2 position of glycerophospholipids. These extracellular proteins have a high disulfide bond content, low molecular mass (14 kDa), and require mM levels of Ca2+ for catalysis. They play a crucial role in the generation of arachidonates and eicosanoids, and have a number of biological actions including immunological responses, inflammation, cellular proliferation, vasoconstriction, and bronchioconstriction.
18 results for "PLA2G7/PAF-AH/Lp-PLA2" in Products
18 results for "PLA2G7/PAF-AH/Lp-PLA2" in Products
PLA2G7/PAF-AH/Lp-PLA2 Products
Secretory phopholipase A2 (PLA2) enzymes cleave an acyl ester bond in the sn-2 position of glycerophospholipids. These extracellular proteins have a high disulfide bond content, low molecular mass (14 kDa), and require mM levels of Ca2+ for catalysis. They play a crucial role in the generation of arachidonates and eicosanoids, and have a number of biological actions including immunological responses, inflammation, cellular proliferation, vasoconstriction, and bronchioconstriction.
Sensitivity: | 0.284 ng/mL |
Applications: | ELISA |
Assay Range: | 0.781 - 50 ng/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma) |
Reactivity: | Human |
Details: | Goat IgG Polyclonal |
Applications: | WB, Simple Western, IP |
Source: | E. coli |
Accession #: | AAH38452 |
Applications: | EnzAct |
For use with catalog number DPLG70
Applications: | ELISA, Ctrl |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #973010 |
Applications: | ELISA |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #973005 |
Applications: | ELISA |
Reactivity: | Human |
Details: | Mouse IgG3 Kappa Monoclonal Clone #5D1 |
Applications: | ELISA, MA |
Applications: | ELISA |
Reactivity: | Human |
Details: | Mouse IgG2b Kappa Monoclonal Clone #D7 |
Applications: | IHC, WB, ICC/IF |
Reactivity: | Human |
Details: | Mouse IgG2b Kappa Monoclonal Clone #D6 |
Applications: | IHC, WB, ICC/IF |
Applications: | WB |
Applications: | ELISA |
Reactivity: | Human |
Details: | Mouse IgG3 Kappa Monoclonal Clone #5B9 |
Applications: | ELISA |
Applications: | PAGE |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | ELISA |
Reactivity: | Mouse |
Details: | Rabbit IgG Polyclonal |
Applications: | ELISA |
Potent lp-PLA2 inhibitor
Chemical Name: | N-[2-(Diethylamino)ethyl]-2-[[(4-fluorophenyl)methyl]thio]-4,5,6,7-tetrahydro-4-oxo-N-[[4'-(trifluoromethyl)[1,1'-biphenyl]-4-yl]methyl]-1H-cyclopentapyrimidine-1-acetamide |
Purity: | ≥98% (HPLC) |
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