Protein Kinase A Inhibitors: Small Molecules and Peptides
The cAMP-dependent protein kinase (PKA) holoenzyme is composed of two regulatory and two catalytic subunits, designated PKA R and PKA C, respectively. Upon PKA R subunit binding to the second messenger cAMP, active PKA C subunits are released, initiating a phosphorylation cascade that regulates such cellular functions as metabolism, ion transport, and gene transcription. Catalytic PKA subunit isoforms, Cα, Cβ and, in humans, Cγ, have been identified.
View small molecule Protein Kinase A Inhibitors, peptide Protein Kinase A Inhibitors and citations by using the filter on the left, or choose one of the products below to view details.
9 results for "Protein Kinase A Inhibitors Small Molecules and Peptides" in Products
9 results for "Protein Kinase A Inhibitors Small Molecules and Peptides" in Products
Protein Kinase A Inhibitors: Small Molecules and Peptides
The cAMP-dependent protein kinase (PKA) holoenzyme is composed of two regulatory and two catalytic subunits, designated PKA R and PKA C, respectively. Upon PKA R subunit binding to the second messenger cAMP, active PKA C subunits are released, initiating a phosphorylation cascade that regulates such cellular functions as metabolism, ion transport, and gene transcription. Catalytic PKA subunit isoforms, Cα, Cβ and, in humans, Cγ, have been identified.
View small molecule Protein Kinase A Inhibitors, peptide Protein Kinase A Inhibitors and citations by using the filter on the left, or choose one of the products below to view details.
Potent protein kinase A inhibitor
| Alternate Names: | Protein kinase inhibitor-(6-22)-amide,PKI-(6-22)-amide |
| Purity: | ≥95% (HPLC) |
Cell-permeable protein kinase A inhibitor
| Alternate Names: | Protein kinase inhibitor-(14-22)-amide,myristoylated |
| Purity: | ≥95% (HPLC) |
Protein kinase A inhibitor
| Chemical Name: | N-[2-[[3-(4-Bromophenyl)-2-propenyl]amino]ethyl]-5-isoquinolinesulfonamide dihydrochloride |
| Purity: | ≥98% (HPLC) |
High affinity PKA inhibitor
| Purity: | ≥95% (HPLC) |
Selective protein kinase A inhibitor
| Chemical Name: | (9R,10S,12S)-2,3,9,10,11,12-Hexahydro-10-hydroxy-9-methyl-1-oxo-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid, hexyl ester |
| Purity: | ≥97% (HPLC) |
Potent pan-Akt and PKA inhibitor
| Chemical Name: | 4-(4-Chlorophenyl)-4-[4-(1H-pyrazol-4-yl)phenyl]piperidine hydrochloride |
| Purity: | ≥98% (HPLC) |
Inhibitor of cyclic nucleotide dependent- and Rho-kinases
| Alternate Names: | HA 1077 |
| Purity: | ≥98% (HPLC) |
cAMP antagonist
| Chemical Name: | (R)-Adenosine, cyclic 3',5'-(hydrogenphosphorothioate) triethylammonium |
| Purity: | ≥98% (HPLC) |
Staurosporine synthesized to Ancillary Material Grade
| Chemical Name: | [9S-(9α,10β,11β,13α)]-2,3,10,11,12,13-Hexahydro-10-methoxy-9-methyl-11-(methylamino)-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one |
| Purity: | ≥98% |
