Pygopus-1 Products
Pygopus-1 and -2 are nuclear transcription co-activators. Structurally they are characterized by an N-terminal homology domain and C-terminal PHD (plant homeodomain) finger Zn2+-binding domain. The PHD finger binds to legless/Bcl9, which in turn binds beta-catenin, a downstream mediator of Wnt signaling. This complex binds TCF/LEF DNA binding proteins. Formation of the quaternary complex is required for the activation of Wnt-responsive genes.
39 results for "Pygopus-1" in Products
39 results for "Pygopus-1" in Products
Pygopus-1 Products
Pygopus-1 and -2 are nuclear transcription co-activators. Structurally they are characterized by an N-terminal homology domain and C-terminal PHD (plant homeodomain) finger Zn2+-binding domain. The PHD finger binds to legless/Bcl9, which in turn binds beta-catenin, a downstream mediator of Wnt signaling. This complex binds TCF/LEF DNA binding proteins. Formation of the quaternary complex is required for the activation of Wnt-responsive genes.
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #466023 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ICC/IF |
![Immunocytochemistry/ Immunofluorescence: Pygopus-1 Antibody [NBP1-86218]](https://resources.bio-techne.com/images/products/Pygopus-1-Antibody-Immunocytochemistry-Immunofluorescence-NBP1-86218-img0004.jpg "Immunocytochemistry/ Immunofluorescence: Pygopus-1 Antibody [NBP1-86218]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, IP, WB (-) |
![Immunohistochemistry: Pygopus-1 Antibody [NBP1-42665]](https://resources.bio-techne.com/images/products/Pygopus-1-Antibody-Immunohistochemistry-NBP1-42665-img0005.jpg "Immunohistochemistry: Pygopus-1 Antibody [NBP1-42665]")
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #3E1 |
| Applications: | WB, ELISA |
![Western Blot: Pygopus-1 Antibody (3E1) [H00026108-M13]](https://resources.bio-techne.com/images/products/Pygopus-1-Antibody-3E1-Western-Blot-H00026108-M13-img0002.jpg "Western Blot: Pygopus-1 Antibody (3E1) [H00026108-M13]")
| Applications: | WB, ELISA, MA, AP |
| Applications: | WB, ELISA, MA, AP |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
![Western Blot: Pygopus-1 Antibody [NBP1-42666]](https://resources.bio-techne.com/images/products/Pygopus-1-Antibody-Western-Blot-NBP1-42666-img0002.jpg "Western Blot: Pygopus-1 Antibody [NBP1-42666]")
| Applications: | WB |
![Western Blot: Pygopus-1 Overexpression Lysate [NBP2-07146]](https://resources.bio-techne.com/images/products/PYGO1-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-07146-img0001.jpg "Western Blot: Pygopus-1 Overexpression Lysate [NBP2-07146]")
| Applications: | AC |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, IP, WB (-) |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, IP, WB (-) |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, IP, WB (-) |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, IP, WB (-) |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, IP, WB (-) |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, IP, WB (-) |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, IP |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, IP, WB (-) |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, IP |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, IP |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, IP |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, IP |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, IP |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, IP, WB (-) |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, IP |