R-Spondin 1 Products
R-Spondin 1 (RSPO1), also known as Cristin 3, is a 27 kDa secreted protein in the R-Spondin family of Wnt/beta-catenin signaling regulators. R-Spondin 1 enhances canonical Wnt/beta-catenin signaling by competing with the Wnt antagonist Dkk-1, binding to Frizzled-8, Kremen, LRP-6, Lgr4, Lgr5, and Lgr6, and enhancing cell surface availability of Wnt receptors. R-Spondin 1 functions in dorsal neural tube development as well as male and female germ cell development. It also induces bone formation, intestinal crypt cell proliferation, angiogenesis, and insulin secretion from pancreatic beta cells.
110 results for "R-Spondin 1" in Products
110 results for "R-Spondin 1" in Products
R-Spondin 1 Products
R-Spondin 1 (RSPO1), also known as Cristin 3, is a 27 kDa secreted protein in the R-Spondin family of Wnt/beta-catenin signaling regulators. R-Spondin 1 enhances canonical Wnt/beta-catenin signaling by competing with the Wnt antagonist Dkk-1, binding to Frizzled-8, Kremen, LRP-6, Lgr4, Lgr5, and Lgr6, and enhancing cell surface availability of Wnt receptors. R-Spondin 1 functions in dorsal neural tube development as well as male and female germ cell development. It also induces bone formation, intestinal crypt cell proliferation, angiogenesis, and insulin secretion from pancreatic beta cells.
| Source: | CHO |
| Accession #: | Q2MKA7 |
| Applications: | BA |
| Source: | CHO |
| Accession #: | NP_619624 |
| Applications: | BA |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #Oncomed patent anti-RSPO1 |
| Applications: | ELISA, Flow, Func |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2B Monoclonal Clone #OTI11A9 |
| Applications: | IHC, WB |
| Assay Range: | 31.2 - 2,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
![Western Blot: R-Spondin 1 AntibodyBSA Free [NBP1-77354]](https://resources.bio-techne.com/images/products/R-Spondin-1-Antibody-Western-Blot-NBP1-77354-img0014.jpg "Western Blot: R-Spondin 1 AntibodyBSA Free [NBP1-77354]")
| Source: | E. coli |
| Accession #: | Q9Z132 |
| Applications: | BA |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC |
| Source: | E. coli |
| Accession #: | Q2MKA7.1 |
| Applications: | BA |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2b Monoclonal Clone #422407 |
| Applications: | WB |
Biotinylated
| Source: | CHO |
| Accession #: | Q2MKA7.1 |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | Neut |
| Source: | CHO |
| Applications: | BA |
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #852010 |
| Applications: | Neut |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2B Monoclonal Clone #OTI11A9 |
| Applications: | IHC, WB |
![Western Blot: R-Spondin 1 Antibody (OTI11A9) [NBP2-45636]](https://resources.bio-techne.com/images/products/R-Spondin-1-Antibody-11A9-Western-Blot-NBP2-45636-img0002.jpg "Western Blot: R-Spondin 1 Antibody (OTI11A9) [NBP2-45636]")
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #Oncomed patent anti-RSPO1 |
| Applications: | ELISA, Flow, Func |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
![Immunohistochemistry-Paraffin: R-Spondin 1 Antibody [NBP1-92357]](https://resources.bio-techne.com/images/products/R-Spondin-1-Antibody-Immunohistochemistry-Paraffin-NBP1-92357-img0006.jpg "Immunohistochemistry-Paraffin: R-Spondin 1 Antibody [NBP1-92357]")
| Applications: | WB |
![Western Blot: R-Spondin 1 Overexpression Lysate [NBP2-08561]](https://resources.bio-techne.com/images/products/RSPO1-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-08561-img0001.jpg "Western Blot: R-Spondin 1 Overexpression Lysate [NBP2-08561]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF |
![Immunocytochemistry/Immunofluorescence: R-Spondin 1 Antibody [NBP3-21297] -](https://resources.bio-techne.com/images/products/nbp3-21297_rabbit-r-spondin-1-pab-45202315514717.jpg "Immunocytochemistry/Immunofluorescence: R-Spondin 1 Antibody [NBP3-21297] -")
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2B Monoclonal Clone #OTI11A9 |
| Applications: | IHC, WB |
| Applications: | AC |
| Applications: | AC |