R-Spondin 1 Products
R-Spondin 1 (RSPO1), also known as Cristin 3, is a 27 kDa secreted protein in the R-Spondin family of Wnt/beta-catenin signaling regulators. R-Spondin 1 enhances canonical Wnt/beta-catenin signaling by competing with the Wnt antagonist Dkk-1, binding to Frizzled-8, Kremen, LRP-6, Lgr4, Lgr5, and Lgr6, and enhancing cell surface availability of Wnt receptors. R-Spondin 1 functions in dorsal neural tube development as well as male and female germ cell development. It also induces bone formation, intestinal crypt cell proliferation, angiogenesis, and insulin secretion from pancreatic beta cells.
83 results for "R-Spondin 1" in Products
83 results for "R-Spondin 1" in Products
R-Spondin 1 Products
R-Spondin 1 (RSPO1), also known as Cristin 3, is a 27 kDa secreted protein in the R-Spondin family of Wnt/beta-catenin signaling regulators. R-Spondin 1 enhances canonical Wnt/beta-catenin signaling by competing with the Wnt antagonist Dkk-1, binding to Frizzled-8, Kremen, LRP-6, Lgr4, Lgr5, and Lgr6, and enhancing cell surface availability of Wnt receptors. R-Spondin 1 functions in dorsal neural tube development as well as male and female germ cell development. It also induces bone formation, intestinal crypt cell proliferation, angiogenesis, and insulin secretion from pancreatic beta cells.
| Source: | CHO |
| Accession #: | Q2MKA7 |
| Applications: | BA |
| Source: | CHO |
| Accession #: | NP_619624 |
| Applications: | BA |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #Oncomed patent anti-RSPO1 |
| Applications: | ELISA, Flow, Func |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC |
| Source: | E. coli |
| Accession #: | Q9Z132 |
| Applications: | BA |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2b Monoclonal Clone #422407 |
| Applications: | WB |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
| Assay Range: | 31.2 - 2,000 pg/mL |
| Applications: | ELISA |
| Source: | E. coli |
| Accession #: | Q2MKA7.1 |
| Applications: | BA |
Biotinylated
| Source: | CHO |
| Accession #: | Q2MKA7.1 |
| Applications: | BA |
| Source: | CHO |
| Applications: | BA |
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #852010 |
| Applications: | Neut |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | Neut |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2B Monoclonal Clone #OTI11A9 |
| Applications: | IHC, WB |
![Western Blot: R-Spondin 1 Antibody (OTI11A9) [NBP2-45636]](https://resources.bio-techne.com/images/products/R-Spondin-1-Antibody-11A9-Western-Blot-NBP2-45636-img0002.jpg "Western Blot: R-Spondin 1 Antibody (OTI11A9) [NBP2-45636]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
![Immunohistochemistry-Paraffin: R-Spondin 1 Antibody [NBP1-92357]](https://resources.bio-techne.com/images/products/R-Spondin-1-Antibody-Immunohistochemistry-Paraffin-NBP1-92357-img0006.jpg "Immunohistochemistry-Paraffin: R-Spondin 1 Antibody [NBP1-92357]")
| Applications: | WB |
![Western Blot: R-Spondin 1 Overexpression Lysate [NBP2-08561]](https://resources.bio-techne.com/images/products/RSPO1-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-08561-img0001.jpg "Western Blot: R-Spondin 1 Overexpression Lysate [NBP2-08561]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF |
![Immunocytochemistry/Immunofluorescence: R-Spondin 1 Antibody [NBP3-21297] -](https://resources.bio-techne.com/images/products/nbp3-21297_rabbit-r-spondin-1-pab-45202315514717.jpg "Immunocytochemistry/Immunofluorescence: R-Spondin 1 Antibody [NBP3-21297] -")
| Applications: | AC |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2B Monoclonal Clone #OTI11A9 |
| Applications: | IHC, WB |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #Oncomed patent anti-RSPO1 |
| Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #Oncomed patent anti-RSPO1 |
| Applications: | ELISA, Flow, Func |