Rad51L1: Proteins and Enzymes

The Rad51 DNA repair protein is a key component of the double-strand break repair pathway and is essential for mitotic and meiotic recombination and genomic stability. Five human RAD51 homologues have been identified: XRCC2, XRCC3, RAD51B, RAD51C, and RAD51D. Each of these homologues interacts with one or more of the others, with all of the proteins involved with one complex or with multiple smaller complexes. Rad51B plays a role in meiotic recombination and/or recombinational repair.