Skp2 Products
SKP2 (S-phase kinase-associated protein 2) is a 45-47 kDa cyclin A- and CDK2-associated phosphoprotein within the FBXL (F-box/LRR) family of ubiquitin ligases, designated FBXL1. As a component of the SCF (SKP1-Cul1-F-box) complex, SKP2 phosphorylation is required for degradation of CDK inhibitors such as p27/Kip1 and progression from G1 to S phases of the cell cycle. Deregulation in cancer promotes cell cycle progression and cancer growth.
68 results for "Skp2" in Products
68 results for "Skp2" in Products
Skp2 Products
SKP2 (S-phase kinase-associated protein 2) is a 45-47 kDa cyclin A- and CDK2-associated phosphoprotein within the FBXL (F-box/LRR) family of ubiquitin ligases, designated FBXL1. As a component of the SCF (SKP1-Cul1-F-box) complex, SKP2 phosphorylation is required for degradation of CDK inhibitors such as p27/Kip1 and progression from G1 to S phases of the cell cycle. Deregulation in cancer promotes cell cycle progression and cancer growth.
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #712120 |
| Applications: | WB, Simple Western |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, KD |
![Western Blot: Skp2 Antibody [NBP2-49142]](https://resources.bio-techne.com/images/products/Skp2-Antibody-Western-Blot-NBP2-49142-img0004.jpg "Western Blot: Skp2 Antibody [NBP2-49142]")
| Applications: | WB, ELISA, MA, AP |
![SDS-PAGE: Recombinant Human Skp2 GST (N-Term) Protein [H00006502-P01]](https://resources.bio-techne.com/images/products/Recombinant-Human-Skp2-Protein-SDS-Page-H00006502-P01-img0002.jpg "SDS-PAGE: Recombinant Human Skp2 GST (N-Term) Protein [H00006502-P01]")
| Applications: | WB, ELISA, MA, AP, PAGE |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #2L0K1 |
| Applications: | IHC, WB |
![Western Blot: Skp2 Antibody (2L0K1) [NBP3-16320]](https://resources.bio-techne.com/images/products/Skp2-Antibody-2L0K1-Western-Blot-NBP3-16320-img0002.jpg "Western Blot: Skp2 Antibody (2L0K1) [NBP3-16320]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #S08-0A2 |
| Applications: | ICC/IF |
![Immunocytochemistry/ Immunofluorescence: Skp2 Antibody (S08-0A2) [NBP3-19917]](https://resources.bio-techne.com/images/products/Skp2-Antibody-S08-0A2-Immunocytochemistry-Immunofluorescence-NBP3-19917-img0001.jpg "Immunocytochemistry/ Immunofluorescence: Skp2 Antibody (S08-0A2) [NBP3-19917]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
![Western Blot: Skp2 Antibody [NBP1-30077]](https://resources.bio-techne.com/images/products/Skp2-Antibody-Western-Blot-NBP1-30077-img0008.jpg "Western Blot: Skp2 Antibody [NBP1-30077]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF, KD |
![Western Blot: Skp2 Antibody [NBP2-56192]](https://resources.bio-techne.com/images/products/Skp2-Antibody-Western-Blot-NBP2-56192-img0002.jpg "Western Blot: Skp2 Antibody [NBP2-56192]")
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #6D4 |
| Applications: | IHC, ELISA, ICC/IF |
![Immunocytochemistry/ Immunofluorescence: Skp2 Antibody (6D4) [NBP3-15203]](https://resources.bio-techne.com/images/products/Skp2-Antibody-6D4-Immunocytochemistry-Immunofluorescence-NBP3-15203-img0001.jpg "Immunocytochemistry/ Immunofluorescence: Skp2 Antibody (6D4) [NBP3-15203]")
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #3C11 |
| Applications: | ELISA, ICC/IF, Flow |
![Immunocytochemistry/ Immunofluorescence: Skp2 Antibody (3C11) [NBP3-15197]](https://resources.bio-techne.com/images/products/Skp2-Antibody-3C11-Immunocytochemistry-Immunofluorescence-NBP3-15197-img0002.jpg "Immunocytochemistry/ Immunofluorescence: Skp2 Antibody (3C11) [NBP3-15197]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF |
![Immunocytochemistry/ Immunofluorescence: Skp2 Antibody [NBP2-97674]](https://resources.bio-techne.com/images/products/Skp2-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-97674-img0001.jpg "Immunocytochemistry/ Immunofluorescence: Skp2 Antibody [NBP2-97674]")
| Applications: | AC |
| Applications: | WB |
![Western Blot: Skp2 Overexpression Lysate [NBL1-15995]](https://resources.bio-techne.com/images/products/SKP2-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-15995-img0002.jpg "Western Blot: Skp2 Overexpression Lysate [NBL1-15995]")
| Applications: | ELISA |
| Applications: | AC |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
SKP2 (S-phase kinase-associated protein 2) inhibitor; upregulates p27 and arrests cell cycle in G1 phase
| Chemical Name: | N-(4-Butyl-2-methylphenyl)acetamide |
| Purity: | ≥98% (HPLC) |
Selective Skp2 inhibitor; suppresses E3 ligase activity
| Chemical Name: | 3-(2-Benzothiazolyl)-6-ethyl-7-hydroxy-8-(1-piperidinylmethyl)-4H-1-benzopyran-4-one |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF |