Sodium Calcium Exchanger 1/NCX1 Products
The plasma membrane Na+/Ca2+ (NaCX) exchangers mediate Na+-dependent Ca2+ efflux in a wide variety of cell types. NaCX can move Ca2+ either into or out of cells, depending on the net Na+, Ca2+, and K+ gradient across the membrane. In mammals, at least 5 distinct genes code for the exchangers: three NaCX (NaCX-1, NaCX-2, and NaCX-3), and two NaCKX (NaCKX-1 and NaCKX-2). NaCX-1 is most prominently expressed in the heart where it plays a major role in excitation-contraction coupling. NACX-1 may also play a role in protecting the heart and brain from ischemia and reperfusion injury.
12 results for "Sodium Calcium Exchanger 1/NCX1" in Products
12 results for "Sodium Calcium Exchanger 1/NCX1" in Products
Sodium Calcium Exchanger 1/NCX1 Products
The plasma membrane Na+/Ca2+ (NaCX) exchangers mediate Na+-dependent Ca2+ efflux in a wide variety of cell types. NaCX can move Ca2+ either into or out of cells, depending on the net Na+, Ca2+, and K+ gradient across the membrane. In mammals, at least 5 distinct genes code for the exchangers: three NaCX (NaCX-1, NaCX-2, and NaCX-3), and two NaCKX (NaCKX-1 and NaCKX-2). NaCX-1 is most prominently expressed in the heart where it plays a major role in excitation-contraction coupling. NACX-1 may also play a role in protecting the heart and brain from ischemia and reperfusion injury.
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Western Blot: Sodium Calcium Exchanger 1/NCX1 AntibodyAzide and BSA Free [NBP2-94316]](https://resources.bio-techne.com/images/products/Sodium-Calcium-Exchanger-1-NCX1-Antibody-Western-Blot-NBP2-94316-img0004.jpg "Western Blot: Sodium Calcium Exchanger 1/NCX1 AntibodyAzide and BSA Free [NBP2-94316]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #SR1046 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF |
![Immunocytochemistry/ Immunofluorescence: Sodium Calcium Exchanger 1/NCX1 Antibody [NBP2-56483]](https://resources.bio-techne.com/images/products/Sodium-Calcium-Exchanger-1-NCX1-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-56483-img0001.jpg "Immunocytochemistry/ Immunofluorescence: Sodium Calcium Exchanger 1/NCX1 Antibody [NBP2-56483]")
| Reactivity: | Human |
| Details: | Rabbit Polyclonal |
| Applications: | WB |
![Western Blot: Sodium Calcium Exchanger 1/NCX1 Antibody [NBP2-83574]](https://resources.bio-techne.com/images/products/Sodium-Calcium-Exchanger-1-NCX1-Antibody-Western-Blot-NBP2-83574-img0001.jpg "Western Blot: Sodium Calcium Exchanger 1/NCX1 Antibody [NBP2-83574]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: Sodium Calcium Exchanger 1/NCX1 AntibodyAzide and BSA Free [NBP2-93088]](https://resources.bio-techne.com/images/products/Sodium-Calcium-Exchanger-1-NCX1-Antibody-Western-Blot-NBP2-93088-img0001.jpg "Western Blot: Sodium Calcium Exchanger 1/NCX1 AntibodyAzide and BSA Free [NBP2-93088]")
| Applications: | AC |
Antagonist of mitochondrial Na+/Ca2+ exchange
| Chemical Name: | 7-Chloro-5-(2-chlorophenyl)-1,5-dihydro-4,1-benzothiazepin-2(3H)-one |
| Purity: | ≥99% (HPLC) |
Na+/Ca2+ exchange inhibitor (reverse mode); neuroprotective
| Chemical Name: | N-[(3-Aminophenyl)methyl]-6-[4-[(3-fluorophenyl)methoxy]phenoxy]-3-pyridinecarboxamide dihydrochloride |
| Purity: | ≥99% (HPLC) |
Non-selective Ca2+ channel blocker; also NCX inhibitor
| Chemical Name: | N-Benzyl-N-(3-isobutoxy-2-pyrrolidin-1-yl-propyl)aniline hydrochloride |
| Purity: | ≥99% (HPLC) |
Na+/Ca2+ exchange inhibitor (reverse mode)
| Chemical Name: | 2-[2-[4-(4-Nitrobenzyloxy)phenyl]ethyl]isothiourea mesylate |
| Purity: | ≥99% (HPLC) |
Selective Na+/Ca2+ exchange inhibitor (reverse mode)
| Chemical Name: | 2-[[4-[(4-Nitrophenyl)methoxy]phenyl]methyl]-4-thiazolidinecarboxylic acid ethyl ester |
| Purity: | ≥99% (HPLC) |
Mitochondrial Na+/Ca2+ exchange (mNCX) inhibitor
| Chemical Name: | 7-Chloro-1,5-dihydro-5-[2-(1-methylethyl)phenyl]-4,1-benzothiazepin-2(3H)-one |
| Purity: | ≥98% (HPLC) |
