TIM-1/KIM-1/HAVCR: Proteins and Enzymes
TIM-1 (T cell immunoglobulin and mucin domain 1), also known as KIM-1 and HAVcr1, is expressed on many immune cell types and epithelial cells. It binds to phosphatidylserine (PS), LMIR5/CD300b, TIM-1 (homophilic), TIM-4, IgA, and the glycoproteins of a number of enveloped viruses. Its interaction with PS enables TIM-1 to mediate the phagocytosis and clearance of apoptotic cells. TIM-1 signaling costimulates T cell activation and enhances Th2 cytokine production. TIM-1 serves as a cellular entry receptor for hepatitis A virus, Ebolavirus and Marburgvirus. Polymorphisms are associated with susceptibility to atopy, autoimmunity, and severe hepatitis A virus infection in humans. A soluble form of TIM-1 is elevated in the urine during nephropathy.
12 results for "TIM-1/KIM-1/HAVCR Proteins and Enzymes" in Products
12 results for "TIM-1/KIM-1/HAVCR Proteins and Enzymes" in Products
TIM-1/KIM-1/HAVCR: Proteins and Enzymes
TIM-1 (T cell immunoglobulin and mucin domain 1), also known as KIM-1 and HAVcr1, is expressed on many immune cell types and epithelial cells. It binds to phosphatidylserine (PS), LMIR5/CD300b, TIM-1 (homophilic), TIM-4, IgA, and the glycoproteins of a number of enveloped viruses. Its interaction with PS enables TIM-1 to mediate the phagocytosis and clearance of apoptotic cells. TIM-1 signaling costimulates T cell activation and enhances Th2 cytokine production. TIM-1 serves as a cellular entry receptor for hepatitis A virus, Ebolavirus and Marburgvirus. Polymorphisms are associated with susceptibility to atopy, autoimmunity, and severe hepatitis A virus infection in humans. A soluble form of TIM-1 is elevated in the urine during nephropathy.
Biotinylated
Source: | HEK293 |
Accession #: | AAC39862.1 |
Applications: | BA, BA, Bind |
Source: | NS0 |
Accession #: | AAC39862 |
Applications: | BA |
This protein is in the process of being discontinued.
Source: | HEK293 |
Accession #: | Q96D42.3 |
Applications: | BA |
Applications: | AC |
Source: | NS0 |
Accession #: | NP_599009.2 |
Applications: | BA, BA |
Source: | NS0 |
Accession #: | O54947 |
Applications: | BA |
(268 aa)
Source: | HEK293 |
Accession #: | AAC39862 |
Applications: | BA |
Source: | NS0 |
Accession #: | NP_599009.2 |
Applications: | BA, BA |
Applications: | AC |
Source: | CHO |
Accession #: | BAJ61042 |
Applications: | BA |
Applications: | PAGE |