Trk Receptor Inhibitors: Small Molecules and Peptides
6 results for "Trk Receptor Inhibitors Small Molecules and Peptides" in Products
6 results for "Trk Receptor Inhibitors Small Molecules and Peptides" in Products
Trk Receptor Inhibitors: Small Molecules and Peptides
Potent Trk inhibitor; inhibits TrkA, TrkB and TrkC
| Chemical Name: | N-[3-[[2,3-Dihydro-2-oxo-3-(1H-pyrrol-2-ylmethylene)-1H-indol-6-yl]amino]-4-methylphenyl]-N'-[2-fluoro-5-(trifluoromethyl)phenyl]urea |
| Purity: | ≥98% (HPLC) |
JAK2, FLT3 and TrkA inhibitor; also inhibits AurA and AurB
| Alternate Names: | CEP-701 |
| Chemical Name: | (9S,10S,12R)-2,3,9,10,11,12-Hexahydro-10-hydroxy-10-(hydroxymethyl)-9-methyl-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocin-1-one |
| Purity: | ≥98% (HPLC) |
Potent, selective TrkA inhibitor
| Chemical Name: | 1,3-Dihydro-3-[(1-methyl-1H-indol-3-yl)methylene]-2H-pyrrolo[3,2-b]pyridin-2-one |
| Purity: | ≥99% (HPLC) |
Selective TrkB receptor agonist; neuroprotectant
| Chemical Name: | N-[2-(5-Hydroxy-1H-indol-3-yl)ethyl]-2-oxo-3-piperidinecarboxamide |
| Purity: | ≥98% (HPLC) |
Potent and selective pan-Trk inhibitor; peripherally restricted
| Chemical Name: | N-[5-[[2-Amino-7-(2-hydroxy-1,1-dimethylethyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]carbonyl]-3-pyridinyl]-5-chloro-2-pyridineacetamide |
| Purity: | ≥98% (HPLC) |
Inhibits NGF binding to p75NTR and TrkA
| Chemical Name: | 2,3,4,10-Tetrahydro-7,10-dimethyl-2,4-dioxobenzo[g]pteridine-8-carboxaldehyde |
| Purity: | ≥95% (HPLC) |
