TTK Products
TTK (Dual specificity Thr/Tyr kinase; also PYT and hMps1) is a 97-105 kDa member of the Ser/Thr protein kinase family of enzymes. It is expressed in rapidly proliferating tissues and cell lines, and participates in cell cycle regulation. In particular, it directs chromosome alignment, centrosome duplication, and spindle assembly checkpoint formation. Via phosphorylation, TTK is known to regulate p53, CDCA8 and TACC2. Human TTK is 857 amino acids (aa) in length and contains one protein kinase domain (aa 525-791). Activation occurs following homodimerization and autophosphorylation on Thr675, Thr676 and Thr686.
73 results for "TTK" in Products
73 results for "TTK" in Products
TTK Products
TTK (Dual specificity Thr/Tyr kinase; also PYT and hMps1) is a 97-105 kDa member of the Ser/Thr protein kinase family of enzymes. It is expressed in rapidly proliferating tissues and cell lines, and participates in cell cycle regulation. In particular, it directs chromosome alignment, centrosome duplication, and spindle assembly checkpoint formation. Via phosphorylation, TTK is known to regulate p53, CDCA8 and TACC2. Human TTK is 857 amino acids (aa) in length and contains one protein kinase domain (aa 525-791). Activation occurs following homodimerization and autophosphorylation on Thr675, Thr676 and Thr686.
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, IHC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #689913 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #4G9 |
| Applications: | WB, ELISA, ICC/IF |
![Western Blot: TTK Antibody (4G9) [H00007272-M02]](https://resources.bio-techne.com/images/products/TTK-Antibody-4G9-Western-Blot-H00007272-M02-img0004.jpg "Western Blot: TTK Antibody (4G9) [H00007272-M02]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, IP, KD |
![Immunoprecipitation: TTK Antibody [NB100-463]](https://resources.bio-techne.com/images/products/TTK-Antibody-NB100-463-img0003.jpg "Immunoprecipitation: TTK Antibody [NB100-463]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ICC/IF |
![Immunocytochemistry/ Immunofluorescence: TTK Antibody [NBP2-98832]](https://resources.bio-techne.com/images/products/TTK-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-98832-img0001.jpg "Immunocytochemistry/ Immunofluorescence: TTK Antibody [NBP2-98832]")
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #3G7 |
| Applications: | WB, ELISA |
![Western Blot: TTK Antibody (3G7) [H00007272-M01]](https://resources.bio-techne.com/images/products/TTK-Antibody-3G7-Western-Blot-H00007272-M01-img0007.jpg "Western Blot: TTK Antibody (3G7) [H00007272-M01]")
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #X1 |
| Applications: | WB, ELISA |
![Western Blot: TTK Antibody (X1) [H00007272-M05]](https://resources.bio-techne.com/images/products/TTK-Antibody-X1-Western-Blot-H00007272-M05-img0002.jpg "Western Blot: TTK Antibody (X1) [H00007272-M05]")
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #2F1 |
| Applications: | WB, ELISA |
![Western Blot: TTK Antibody (2F1) [H00007272-M04]](https://resources.bio-techne.com/images/products/TTK-Antibody-2F1-Western-Blot-H00007272-M04-img0004.jpg "Western Blot: TTK Antibody (2F1) [H00007272-M04]")
| Applications: | Bioactivity, PAGE, Binding Activity |
![SDS-PAGE: Recombinant Human TTK His-GST Protein [P4790]](https://resources.bio-techne.com/images/products/Recombinant-Human-TTK-Protein-SDS-Page-P4790-img0001.jpg "SDS-PAGE: Recombinant Human TTK His-GST Protein [P4790]")
| Applications: | WB |
![Western Blot: TTK Overexpression Lysate [NBL1-17415]](https://resources.bio-techne.com/images/products/TTK-protein-kinase-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-17415-img0002.jpg "Western Blot: TTK Overexpression Lysate [NBL1-17415]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ICC/IF |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, IP, KD |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, IP, KD |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ICC/IF |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ICC/IF |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, IP, KD |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, IP, KD |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ICC/IF |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ICC/IF |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, IP, KD |
Potent and selective Mps1 kinase inhibitor
| Chemical Name: | 9-Cyclopentyl-2-[[2-methoxy-4-[(1-methylpiperidin-4-yl)oxy]-phenyl]amino]-7-methyl-7,9-dihydro-8H-purin-8-one |
| Purity: | ≥99% (HPLC) |
Selective Mps1 kinase inhibitor
| Chemical Name: | 1-[3-Methoxy-4-[[4-[[2-[(1-methylethyl)sulfonyl]phenyl]amino]-1H-pyrrolo[2,3-b]pyridin-6-yl]amino]phenyl]-4-piperidinol dihydrochloride |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, IP |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, IP |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, IP |