ZMPSTE24: Proteins and Enzymes
ZMPSTE24, also known as FACE1, is a zinc metalloprotease involved in the post-translational processing of Lamin A/C precursors. Specifically, ZMPSTE-24 proteolytically removes the C-terminal three residues of the farnesylated Lamin proteins.
FACE-1 is widely expressed, with the highest levels found in the kidney, prostate, testis and ovary.
Mutations in ZMPSTE24 have been associated with human diseases such as mandibuloacral dysplasia with type B lipodystrophy (MADB) and lethal tight skin contracture syndrome (LTSCS), often due to the accumulation of LMNA precursors. It is theorized that ZMPSTE24 may play an important role in human ageing, based on its association with LMNA.
Show More
FACE-1 is widely expressed, with the highest levels found in the kidney, prostate, testis and ovary.
Mutations in ZMPSTE24 have been associated with human diseases such as mandibuloacral dysplasia with type B lipodystrophy (MADB) and lethal tight skin contracture syndrome (LTSCS), often due to the accumulation of LMNA precursors. It is theorized that ZMPSTE24 may play an important role in human ageing, based on its association with LMNA.
4 results for "ZMPSTE24 Proteins and Enzymes" in Products
4 results for "ZMPSTE24 Proteins and Enzymes" in Products
ZMPSTE24: Proteins and Enzymes
ZMPSTE24, also known as FACE1, is a zinc metalloprotease involved in the post-translational processing of Lamin A/C precursors. Specifically, ZMPSTE-24 proteolytically removes the C-terminal three residues of the farnesylated Lamin proteins.
FACE-1 is widely expressed, with the highest levels found in the kidney, prostate, testis and ovary.
Mutations in ZMPSTE24 have been associated with human diseases such as mandibuloacral dysplasia with type B lipodystrophy (MADB) and lethal tight skin contracture syndrome (LTSCS), often due to the accumulation of LMNA precursors. It is theorized that ZMPSTE24 may play an important role in human ageing, based on its association with LMNA.
Show More
FACE-1 is widely expressed, with the highest levels found in the kidney, prostate, testis and ovary.
Mutations in ZMPSTE24 have been associated with human diseases such as mandibuloacral dysplasia with type B lipodystrophy (MADB) and lethal tight skin contracture syndrome (LTSCS), often due to the accumulation of LMNA precursors. It is theorized that ZMPSTE24 may play an important role in human ageing, based on its association with LMNA.
| Applications: | AC |
| Applications: | WB, ELISA, MA, AP |
| Applications: | WB, ELISA, MA, AP |
| Applications: | AC |