CEACAM1/CD66a Antibody (CC1) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-43390

Novus Biologicals, part of Bio-Techne
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NBP1-43390-0.1mg
NBP1-43390-0.025mg
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Key Product Details

Species Reactivity

Validated:

Mouse

Cited:

Mouse

Applications

Validated:

Block/Neutralize, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Immunoprecipitation, In vitro assay, Western Blot

Cited:

Block/Neutralize, Flow Cytometry, Immunohistochemistry-Frozen, Immunoprecipitation, In vitro assay, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CC1

Format

BSA Free

Concentration

5 mg/ml

View all CEACAM-1/CD66a Antibodies »

Product Specifications

Immunogen

The immunogen for this antibody was CD66a.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for CEACAM1/CD66a Antibody (CC1) - BSA Free

Immunoprecipitation: CEACAM1/CD66a Antibody (CC1) - BSA Free [NBP1-43390]

Immunoprecipitation: CEACAM1/CD66a Antibody (CC1) - BSA Free [NBP1-43390]

Immunoprecipitation: CEACAM1/CD66a Antibody (CC1) [NBP1-43390] - CEACAM1 interacts with Syk. Immunoblot analysis of CEACAM1, Syk, and GAPDH in mouse B-lymphocyte from whole cell lysate and after immunoprecipitation with or without anti-CEACAM1 antibody (mAb, CC1). Data are representative of 3 independent experiments. Image collected and cropped by CiteAb from the following publication (nature.com/articles/ncomms7217) licensed under a CC-BY license.

Applications for CEACAM1/CD66a Antibody (CC1) - BSA Free

Application
Recommended Usage

Flow Cytometry

1:10-1:1000

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500
Application Notes
This CC1 antibody has been tested by flow cytometric analysis of mouse splenocytes. This can be used at less than or equal to 0.25 ug per test. Cell number should be determined empirically but can range from 10^5to 10^8cells/test. Use in Immunohistochemistry-Frozen, Immunoprecipitation, western blot, In vitro assay, blocking / neutralizing, and FLOW reported in scientific literature (PMID 25692415). Use in ICC/IF was reported in scientific literature (PMID: 25692415).

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS (pH 7.2)

Format

BSA Free

Preservative

0.09% Sodium Azide

Concentration

5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: CEACAM-1/CD66a

CEACAM1 (BGP) belongs to the carcinoembryonic antigen (CEA) gene family. It is expressed on cells of epithelial and myeloid origin. CEACAM1 expression is downregulated in many tumors indicating a tumor - suppressive function. The antitumor effect may be due to inhibition of tumor angiogenesis, possibly by increased secretion of antiangiogenic molecules from the cells. Like all members of the CEACAM family, it consists of a single N domain, with structural homology to the immunoglobulin variable domains, followed by two immunoglobulin constant-like A (A1, A2) and one B domain. While the N, A1 and B domains can also be found in other CEA-family members, the A2 domain of CEACAM1 differs from those found in other CEACAM.

Long Name

Carcinoembryonic Antigen-related Cell Adhesion Molecule 1

Alternate Names

BGP1, Biliary Glycoprotein 1, CD66a, Cea-1, CEACAM1, Hv-1, Hv-2, MHVR

Entrez Gene IDs

1048 (Human)

Gene Symbol

CEACAM5

UniProt

P06731

Additional CEACAM-1/CD66a Products

Product Documents for CEACAM1/CD66a Antibody (CC1) - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CEACAM1/CD66a Antibody (CC1) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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