Chromogranin A Antibody (SPM553) [CoraFluor™ 1]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-34795CL1

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Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Unconjugated

NBP2-32955

Alexa Fluor 350

NBP2-34795AF350

Alexa Fluor 405

NBP2-34795AF405

Alexa Fluor 488

NBP2-34795AF488

Alexa Fluor 532

NBP2-34795AF532

Alexa Fluor 594

NBP2-34795AF594

Alexa Fluor 647

NBP2-34795AF647

Alexa Fluor 700

NBP2-34795AF700

Alexa Fluor 750

NBP2-34795AF750

Allophycocyanin

NBP2-34795APC

Biotin

NBP2-34795B

DyLight 350

NBP2-34795UV

DyLight 405

NBP2-34795V

DyLight 488

NBP2-34795G

DyLight 550

NBP2-34795R

DyLight 594

NBP2-34795DL594

DyLight 650

NBP2-34795C

DyLight 680

NBP2-34795FR

DyLight 755

NBP2-34795IR

FITC

NBP2-34795F

HRP

NBP2-34795H

Janelia Fluor 525

NBP2-34795JF525

Janelia Fluor 549

NBP2-34795JF549

Janelia Fluor 646

NBP2-34795JF646

Janelia Fluor 669

NBP2-34795JF669

mFluor Violet 450 SE

NBP2-34795MFV450

mFluor Violet 500 SE

NBP2-34795MFV500

mFluor Violet 610 SE

NBP2-34795MFV610

PE

NBP2-34795PE

PerCP

NBP2-34795PCP

Forumulation

Catalog #

Azide and BSA Free

NBP2-34795

IHC-Prediluted

NBP2-44766

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human

Applications

CyTOF-ready, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

CoraFluor 1

Antibody Source

Monoclonal Mouse IgG₁ kappa Clone # SPM553

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Chromogranin A Antibodies »

Product Specifications

Immunogen

Recombinant human chromogranin A protein (Uniprot: P10645)

Localization

Finely granular cytoplasmic

Marker

Neuroendocrine Marker

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₁ kappa

Description

CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.

Applications for Chromogranin A Antibody (SPM553) [CoraFluor™ 1]

Application

Recommended Usage

CyTOF-ready

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark. Do not freeze.

Background: Chromogranin A

Chromogranin A (CgA) is an 86 kDa protein that is the major member of the granin family of acidic secretory glycoproteins located in neuroendocrine cells. CgA is believed to play a role in targeting peptide hormones and neurotransmitters to granules of the regulated pathways and inhibit hormone and neurotransmitter release. Also, the widespread distribution of CgA has made the measurement of circulating immunoreactive CgA a valuable tool in the diagnosis of neuroendocrine neoplasia, and CgA immunohistochemistry can help to identify the neuroendocrine nature of tumors. The N-terminal domain of CgA inhibits tumor necrosis factor a (TNFa) induced gap formation in human umbilical venous endothelial cells. CgA levels which reflect neuroendocrine differentiation of prostatic carcinoma may have a diagnostic, therapeutic and prognostic role in the management of prostate cancer patients.

Alternate Names

Betagranin, Catestatin, CHGA, Chromofungin, Pancreastatin, Parastatin, Parathyroid Secretory Protein 1, Pituitary Secretory Protein I, SP-I

Gene Symbol

CHGA

Additional Chromogranin A Products

Product Documents for Chromogranin A Antibody (SPM553) [CoraFluor™ 1]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for Chromogranin A Antibody (SPM553) [CoraFluor™ 1]

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations
Reviews

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