EDA-A1/Ectodysplasin A1 Antibody [DyLight 488]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-81908G

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

DyLight 488 (Excitation = 493 nm, Emission = 518 nm)

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all EDA-A1/Ectodysplasin A1 Antibodies »

Product Summary for EDA-A1/Ectodysplasin A1 Antibody [DyLight 488]

Immunogen

EDA-A1 antibody was raised against an 19 amino acid peptide near the center of human EDA-A1. The immunogen is located within amino acids 130 - 180 of EDA-A1. Amino Acid Squence: PDEKPYSEEESRRVRRNKR

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Bovine: (89%)

Specificity

EDA-A1/Ectodysplasin A1 antibody is human, mouse and rat reactive. Multiple isoforms of EDA-A1/Ectodysplasin A1 are known to exist.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for EDA-A1/Ectodysplasin A1 Antibody [DyLight 488]

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: EDA-A1/Ectodysplasin A1

Ectodysplasin-A1 (EDA-A1) is a type II transmembrane protein belonging to the TNF superfamily. It is one of multiple isoforms encoded by the EDA gene. Human EDA-A1 is a 391 amino acid protein with a predicted molecular mass of 41 kDa. Mouse and rat EDA-A1 share 94% amino acid sequence identity with the human protein. EDA-A1 is expressed by keratinocytes, hair follicles, and sweat glands, where it can be localized to the cell surface or cleaved into a soluble form by Furin. EDA-A1 forms a homotrimeric protein that binds to EDAR and activates NF-kappa B signaling. Mutations in EDA are associated with a group of developmental disorders identified as ectodermal dysplasia type 1.

Alternate Names

EDAA1

Gene Symbol

EDA

Additional EDA-A1/Ectodysplasin A1 Products

Product Documents for EDA-A1/Ectodysplasin A1 Antibody [DyLight 488]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for EDA-A1/Ectodysplasin A1 Antibody [DyLight 488]



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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