EDA-A1/Ectodysplasin A1 Products
Ectodysplasin-A1 (EDA-A1) is a type II transmembrane protein belonging to the TNF superfamily. It is one of multiple isoforms encoded by the EDA gene. Human EDA-A1 is a 391 amino acid protein with a predicted molecular mass of 41 kDa. Mouse and rat EDA-A1 share 94% amino acid sequence identity with the human protein. EDA-A1 is expressed by keratinocytes, hair follicles, and sweat glands, where it can be localized to the cell surface or cleaved into a soluble form by Furin. EDA-A1 forms a homotrimeric protein that binds to EDAR and activates NF-kappa B signaling. Mutations in EDA are associated with a group of developmental disorders identified as ectodermal dysplasia type 1.
36 results for "EDA-A1/Ectodysplasin A1" in Products
36 results for "EDA-A1/Ectodysplasin A1" in Products
EDA-A1/Ectodysplasin A1 Products
Ectodysplasin-A1 (EDA-A1) is a type II transmembrane protein belonging to the TNF superfamily. It is one of multiple isoforms encoded by the EDA gene. Human EDA-A1 is a 391 amino acid protein with a predicted molecular mass of 41 kDa. Mouse and rat EDA-A1 share 94% amino acid sequence identity with the human protein. EDA-A1 is expressed by keratinocytes, hair follicles, and sweat glands, where it can be localized to the cell surface or cleaved into a soluble form by Furin. EDA-A1 forms a homotrimeric protein that binds to EDAR and activates NF-kappa B signaling. Mutations in EDA are associated with a group of developmental disorders identified as ectodermal dysplasia type 1.
Source: | NS0 |
Accession #: | Q92838 |
Applications: | Bind |
Source: | NS0 |
Accession #: | O54693 |
Applications: | Bind |
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ELISA, ICC/IF |
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ELISA, ICC/IF |
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ELISA, ICC/IF |
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ELISA, ICC/IF |
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ELISA, ICC/IF |
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ELISA, ICC/IF |
Assay Range: | 93.8 - 6,000 pg/mL |
Applications: | ELISA |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #174806 |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #174817 |
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ELISA, ICC/IF |
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ELISA, ICC/IF |
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ELISA, ICC/IF |
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ELISA, ICC/IF |
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ELISA, ICC/IF |
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ELISA, ICC/IF |
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ELISA, ICC/IF |
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ELISA, ICC/IF |
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ELISA, ICC/IF |
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ELISA, ICC/IF |
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ELISA, ICC/IF |
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ELISA, ICC/IF |
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ELISA, ICC/IF |
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ELISA, ICC/IF |