Human/Mouse/Rat/Chicken Oligodendrocyte Marker O4 PE‑conjugated Antibody
R&D Systems, part of Bio-Techne | Catalog # FAB1326P
Conjugate
Catalog #
Key Product Details
Species Reactivity
Validated:
Human, Mouse, Rat, Chicken
Cited:
Human, Mouse, Rat, Transgenic Mouse
Applications
Validated:
Flow Cytometry
Cited:
Flow Cytometry
Label
Phycoerythrin (Excitation = 488 nm, Emission = 565-605 nm)
Antibody Source
Monoclonal Mouse IgM Clone # O4
Product Specifications
Immunogen
Bovine brain corpus callosum white matter
Specificity
Detects human, mouse, rat, and chicken Oligodendrocyte Marker O4.
Clonality
Monoclonal
Host
Mouse
Isotype
IgM
Scientific Data Images
Detection of Oligodendrocyte Marker O4 in Rat Cortical Stem Cells by Flow Cytometry.
Rat cortical stem cells either differentiated (filled histogram) or undifferentiated (open histogram) were stained with Mouse Anti-Human/Mouse/Rat/ Chicken Oligodendrocyte Marker O4 PE‑conjugated Monoclonal Antibody (Catalog # FAB1326P). View our protocol for Staining Membrane-associated Proteins.Applications
Application
Recommended Usage
Flow Cytometry
10 µL/106 cells
Sample: Differentiated rat cortical stem cells
Sample: Differentiated rat cortical stem cells
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
IgM-specific Affinity-purified from hybridoma culture supernatant
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.
Background: Oligodendrocyte Marker O4
Oligodendrocytes are myelinating cells in the central nervous system (CNS) and form the myelin sheath of axons to support rapid nerve conduction. Oligodendrocyte Marker O4 is an antigen on the surface of oligodendrocyte progenitors (1, 2). It has been commonly used as the earliest recognized marker specific for the oligodendroglial lineage (3-8).
References
- Schachner, M. et al. (1981) Dev. Biol. 83:328.
- Bansal, R. et al. (1989) J. Neurosci. Res. 24:548.
- Bansal, R. and Pfeiffer, S.E. (1989) Proc. Natl. Acad. Sci. USA 86:6181.
- Gard, A. et al. (1995) Dev. Biol. 167:596.
- Reynolds, R. and Hardy, R. (1997) J. Neurosci. Res. 47:455.
- Ono, K. et al. (1997) J. Neurosci. Res. 48:212.
- Pang, Y. et al. (2000) J. Neurosci. Res. 62:510.
- Cai, Z. et al. (2001) Brain Res. 898:126.
Additional Oligodendrocyte Marker O4 Products
Product Specific Notices
For research use only
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