Oligodendrocyte Marker O4 NorthernLights™ NL493-conjugated Antibody
R&D Systems, part of Bio-Techne | Catalog # NL1326G
Conjugate
Catalog #
Key Product Details
Species Reactivity
Validated:
Human, Mouse, Rat, Chicken
Applications
Immunocytochemistry
Label
NL493 (Excitation = 493 nm, Emission = 514 nm)
Antibody Source
Monoclonal Mouse IgM Clone # O4
Product Summary for Oligodendrocyte Marker O4 NorthernLights™ NL493-conjugated Antibody
Specificity
Detects human, mouse, rat, and chicken Oligodendrocyte Marker O4.
Clonality
Monoclonal
Host
Mouse
Isotype
IgM
Applications for Oligodendrocyte Marker O4 NorthernLights™ NL493-conjugated Antibody
Application
Recommended Usage
Immunocytochemistry
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.
Background: Oligodendrocyte Marker O4
Oligodendrocytes are myelinating cells in the central nervous system (CNS) and form the myelin sheath of axons to support rapid nerve conduction. Oligodendrocyte Marker O4 is an antigen on the surface of oligodendrocyte progenitors (1, 2). It has been commonly used as the earliest recognized marker specific for the oligodendroglial lineage (3-8).
References
- Schachner, M. et al. (1981) Dev. Biol. 83:328.
- Bansal, R. et al. (1989) J. Neurosci. Res. 24:548.
- Bansal, R. and Pfeiffer, S.E. (1989) Proc. Natl. Acad. Sci. USA 86:6181.
- Gard, A. et al. (1995) Dev. Biol. 167:596.
- Reynolds, R. and Hardy, R. (1997) J. Neurosci. Res. 47:455.
- Ono, K. et al. (1997) J. Neurosci. Res. 48:212.
- Pang, Y. et al. (2000) J. Neurosci. Res. 62:510.
- Cai, Z. et al. (2001) Brain Res. 898:126.
Additional Oligodendrocyte Marker O4 Products
Product Specific Notices for Oligodendrocyte Marker O4 NorthernLights™ NL493-conjugated Antibody
For research use only
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