IkB-alpha [p Ser36] Antibody (39A1413) [DyLight 594]

Novus Biologicals, part of Bio-Techne | Catalog # NB100-56724DL594

Submit a review

Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Alexa Fluor 350

NB100-56724AF350

Alexa Fluor 405

NB100-56724AF405

Alexa Fluor 488

NB100-56724AF488

Alexa Fluor 532

NB100-56724AF532

Alexa Fluor 594

NB100-56724AF594

Alexa Fluor 647

NB100-56724AF647

Alexa Fluor 700

NB100-56724AF700

Alexa Fluor 750

NB100-56724AF750

Biotin

NB100-56065

Biotin

NB100-56724B

DyLight 350

NB100-56724UV

DyLight 405

NB100-56724V

DyLight 488

NB100-56724G

DyLight 550

NB100-56724R

DyLight 650

NB100-56724C

DyLight 680

NB100-56724FR

DyLight 755

NB100-56724IR

FITC

NB100-56724F

HRP

NB100-56724H

Janelia Fluor 549

NB100-56724JF549

Janelia Fluor 646

NB100-56724JF646

mFluor Violet 450 SE

NB100-56724MFV450

mFluor Violet 500 SE

NB100-56724MFV500

mFluor Violet 610 SE

NB100-56724MFV610

Forumulation

Catalog #

BSA Free

NB100-56724

Azide Free

NBP2-33247

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human, Mouse, Rat, Porcine, Bovine, Canine

Applications

Immunoprecipitation, Simple Western, Western Blot

Label

DyLight 594 (Excitation = 593 nm, Emission = 618 nm)

Antibody Source

Monoclonal Mouse IgG₁ kappa Clone # 39A1413

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all IkB-alpha Antibodies »

Product Specifications

Immunogen

This monoclonal antibody was raised against a synthetic peptide containing phosphorylated serines at amino acid residues 32 and 36 of human IkBa.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₁ kappa

Applications for IkB-alpha [p Ser36] Antibody (39A1413) [DyLight 594]

Application

Recommended Usage

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Simple Western

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: IkB-alpha

NF-kB is silenced in the cytoplasm by an inhibitory protein, IkB (1). Synthesis of IkBa is autoregulated (2). IkB proteins are phosphorylated by IkB kinase complex consisting of at least three proteins, IKK1/a, IKK2/b, and IKK3/g (3-6). External stimuli such as tumor necrosis factor or other cytokines results in phosphorylation and degradation of IkB releasing NF-kB dimers. NF-kB dimer subsequently translocates to the nucleus and activates target genes. Six members of IkB family members have been identified (1). One of the first gene induced following NF-kB activation is IkBa.

Long Name

I-kappa-B-alpha

Alternate Names

IkBalpha, MAD-3, NFKBIA

Gene Symbol

NFKBIA

Additional IkB-alpha Products

Product Documents for IkB-alpha [p Ser36] Antibody (39A1413) [DyLight 594]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for IkB-alpha [p Ser36] Antibody (39A1413) [DyLight 594]

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations
Reviews