Integrin alpha V beta 3 Antibody (23C6) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-80816

Novus Biologicals, part of Bio-Techne
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NBP2-80816
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Catalog #
BSA Free
NB100-2677
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Key Product Details

Species Reactivity

Human

Applications

CyTOF-ready, Flow Cytometry, Immunohistochemistry, Immunoprecipitation

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 23C6

Format

Azide and BSA Free

Concentration

1 mg/ml

View all Integrin alpha V beta 3 Antibodies »

Product Specifications

Immunogen

A cell suspension containing osteoclasts from osteoclastomas.

Localization

Cell Membrane

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for Integrin alpha V beta 3 Antibody (23C6) - Azide and BSA Free

Application
Recommended Usage

Flow Cytometry

2.5 ug/10^6 cells

Immunohistochemistry

1:10 - 1:500

Immunoprecipitation

1:10 - 1:500
Application Notes
Positive control(s): Tonsil.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Integrin alpha V beta 3

Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits, which mediate cell-cell and cell-extracellular matrix attachments. Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells. Integrin alpha V beta 3 is the predominant integrin of osteoclasts (bone resorbing cells) and is upregulated in malignant melanoma. Integrin alpha V beta 3 binds to a range of ECM proteins (e.g. vitronectin, fibrinogen, fibronectin) via an Arg-Gly-Asp (RGD) motif.

Alternate Names

antigen identified by monoclonal L230, CD51, CD51 antigen, integrin alpha-V, integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51), MSK8, Vitronectin receptor subunit alpha, VNRADKFZp686A08142

Gene Symbol

ITGAV

Additional Integrin alpha V beta 3 Products

Product Documents for Integrin alpha V beta 3 Antibody (23C6) - Azide and BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Integrin alpha V beta 3 Antibody (23C6) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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