Mouse Glut2 APC-conjugated Antibody
R&D Systems, part of Bio-Techne | Catalog # FAB1440A
Conjugate
Catalog #
Key Product Details
Species Reactivity
Validated:
Mouse
Cited:
Mouse
Applications
Validated:
Flow Cytometry
Cited:
Flow Cytometry, Immunocytochemistry
Label
Allophycocyanin (Excitation = 620-650 nm, Emission = 660-670 nm)
Antibody Source
Monoclonal Rat IgG2B Clone # 205115
Product Specifications
Immunogen
CHO Chinese hamster ovary cell line transfected with mouse Glut2
Met1-Val523
Accession # P14246
Met1-Val523
Accession # P14246
Specificity
Detects mouse Glut2. Recognizes mouse Glut2-transfected NS0 cells but not NS0 control transfectants. It also detects Glut2 on mouse insulinoma betaTC-6 cells (1).
Clonality
Monoclonal
Host
Rat
Isotype
IgG2B
Scientific Data Images for Mouse Glut2 APC-conjugated Antibody
Detection of Glut2 in betaTC‑6 Mouse Cell Line by Flow Cytometry.
betaTC-6 mouse beta cell insulinoma cell line was stained with Rat Anti-Mouse Glut2 APC-conjugated Monoclonal Antibody (Catalog # FAB1440A, filled histogram) or isotype control antibody (Catalog # IC013A, open histogram). View our protocol for Staining Membrane-associated Proteins.Applications for Mouse Glut2 APC-conjugated Antibody
Application
Recommended Usage
Flow Cytometry
0.25-1 µg/106 cells
Sample: betaTC‑6 mouse beta cell insulinoma cell line
Sample: betaTC‑6 mouse beta cell insulinoma cell line
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.
Background: Glut2
Glut2, also known as SLC2A2, belongs to the facilitative glucose transporter protein family that comprises 13 members. It is an integral membrane glycoprotein with 12 transmembrane domains. Glut2 is expressed predominantly in liver, intestine, kidney and pancreatic beta-cells. It is a low-affinity glucose transporter that has been suggested to function as a glucose sensor in pancreatic beta-cells, and facilitate either glucose uptake or efflux from cells depending on the nutritional state (1, 2).
References
-
Poitout, V. et al. (1995) Diabetes 44:306.
- Olson, A.L. and J.E. Pessin (1996) Annu. Rev. Nut. 16:235.
Long Name
Glucose Transporter Type 2
Alternate Names
SLC2A2
Gene Symbol
SLC2A2
UniProt
Additional Glut2 Products
Product Documents for Mouse Glut2 APC-conjugated Antibody
Product Specific Notices for Mouse Glut2 APC-conjugated Antibody
For research use only
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