p40/deltaNp63 Antibody (P40/8225R) [Janelia Fluor® 635]
Novus Biologicals, part of Bio-Techne | Catalog # NBP3-20793JF635
Recombinant Monoclonal Antibody
Conjugate
Catalog #
Forumulation
Catalog #
Key Product Details
Species Reactivity
Validated:
Human
Applications
Immunohistochemistry-Paraffin
Label
Janelia Fluor 635
Antibody Source
Recombinant Monoclonal Rabbit IgG Kappa Clone # P40/8225R
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Summary for p40/deltaNp63 Antibody (P40/8225R) [Janelia Fluor® 635]
Immunogen
Recombinant fragment (around aa1-200) of human p40/deltaNp63 protein (exact sequence is proprietary)
Localization
Nucleus.
Specificity
The p40 (clone P40/8225R) antibody recognizes exclusively delta-Np63 but not TAp63 p40 is a squamous cell carcinoma specific antibody It reacts with the vast majority of cases of squamous cell carcinomas of various origins, but not with adenocarcinomas It is particularly useful in differentiating lung squamous cell carcinoma from lung poorly differentiated adenocarcinoma p40 antibody can also be used as an alternative basal cell/myoepithelial cell marker, which has similar sensitivity and specificity as that of p63 antibody Therefore, p40 antibody may also be used as an alternative immunohistochemical marker for determining prostate adenocarcinoma vs benign prostate glands and for determining breast intraductal carcinoma vs invasive breast ductal carcinoma
Clonality
Monoclonal
Host
Rabbit
Isotype
IgG Kappa
Applications for p40/deltaNp63 Antibody (P40/8225R) [Janelia Fluor® 635]
Application
Recommended Usage
Immunohistochemistry-Paraffin
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A purified
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: p40/deltaNp63
Alternate Names
AIS, amplified in squamous cell carcinoma, B(p51A), B(p51B), Chronic ulcerative stomatitis protein, EEC3, Keratinocyte transcription factor KET, KET, LMS, OFC8, p53CP, SHFM4, TP53CP, TP53L, TP63, TP73L, Transformation-related protein 63, tumor protein p53-competing protein
Gene Symbol
TP63
Additional p40/deltaNp63 Products
Product Documents for p40/deltaNp63 Antibody (P40/8225R) [Janelia Fluor® 635]
Product Specific Notices for p40/deltaNp63 Antibody (P40/8225R) [Janelia Fluor® 635]
Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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