Cyclosporin H

Name: Cyclosporin H
Brand: Tocris Bioscience
SKU: 6982

Tocris Bioscience, part of Bio-Techne | Catalog # 6982

Citations (3)

COA / SDS

Enhances lentiviral transduction

Key Product Details

Chemical Name:	5-(N-Methyl-D-valine)cyclosporin A
Purity:	≥97%

View Full Technical Details for Cyclosporin H

Technical Data
Citations

Biological Activity for Cyclosporin H

Cyclosporin H is a viral transduction enhancer. Increases lentiviral transduction up to 10-fold in human cord blood-derived hematopoietic stem and progenitor cells (HSPCs). Displays an additive effect when combined with rapamycin (Cat. No. 1292) or prostaglandin E₂ (Cat. No. 2296). Lacks immunosuppressant activity of cyclosporin A (Cat. No. 1101).

Technical Data for Cyclosporin H

Formula	C₆₂H₁₁₁N₁₁O₁₂
Storage	Store at -20°C
Purity	≥97%
CAS Number	83602-39-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Cyclosporin H

Solubility

Soluble Soluble to 100 mM in DMSO and to 50 mM in ethanol

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

References for Cyclosporin H

References are publications that support the biological activity of the product.

Petrillo et al. Cyclosporine H overcomes innate immune restrictions to improve lentiviral transduction and gene editing in human hematopoietic stem cells. Cell Stem Cell., 2018;23:820 PMID: 30416070

Cyclosporin H

Tocris Bioscience, part of Bio-Techne | Catalog # 6982

Key Product Details

Biological Activity for Cyclosporin H

Technical Data for Cyclosporin H

Solubility for Cyclosporin H

Dilution Calculator

Reconstitution Calculator

References for Cyclosporin H

Product Documents for Cyclosporin H

COA

Certificate of Analysis

SDS

CONTACT INFORMATION

Stay Connected