3322 results for "Ubiquitin E3 ligase" in Products
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3322 results for "Ubiquitin E3 ligase" in Products
Potent and selective degrader of mutant FKBP12F36V fusion proteins
| Chemical Name: | (R)-3-(3,4-Dimethoxyphenyl)-1-(2-(2-((7-(((S)-1-((2S,4R)-4-hydroxy-2-(((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-7-oxoheptyl)amino)-2-oxoethoxy)phenyl)propyl (S)-1-((S)-2-(3,4,5-trimethoxyphenyl)butanoyl)piperidine-2-carboxylate trifluoroacetate |
| Purity: | ≥98% (HPLC) |
Inhibitor of Bmi1/Ring1A; blocks histone H2A ubiquitination
| Chemical Name: | 2-(3-Pyridinylmethylene)-1H-Indene-1,3(2H)-dione |
| Purity: | ≥99% (HPLC) |
Contains 4 membranes-each spotted in duplicate with 49 different antibodies to ubiquitin target proteins
| Source: | Sf 21 (baculovirus) |
| Accession #: | P40337.2, Q15370.1, Q15369.1, Q13617.2, P62877.1 |
| Applications: | BA |
| Source: | Sf 21 (baculovirus) |
| Accession #: | Q13616.2 (CUL1), P62877.1 (RBX1) |
| Applications: | BA |
| Reactivity: | Human, Mouse, Hamster |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, IP, KO |
![Western Blot: HRD1 AntibodyBSA Free [NB100-2526]](https://resources.bio-techne.com/images/products/HRD1-Antibody-Western-Blot-NB100-2526-img0006.jpg "Western Blot: HRD1 AntibodyBSA Free [NB100-2526]")
(4)
Conjugate
Catalog #
Cereblon binder; induces ubiquitination and degradation of CK1α by E3 ubiquitin ligase
| Chemical Name: | 3-(4-Amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione |
| Purity: | ≥98% (HPLC) |
Selective Skp2 inhibitor; suppresses E3 ligase activity
| Chemical Name: | 3-(2-Benzothiazolyl)-6-ethyl-7-hydroxy-8-(1-piperidinylmethyl)-4H-1-benzopyran-4-one |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, IHC, ICC |
(3)
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #875227 |
| Applications: | WB, Simple Western, ICC |
(3)