Skip to main content

B7-2/CD86 Products

B7-2/CD86 and the related B7-1/CD80 are transmembrane cell surface molecules that play important roles in immune activation and the maintenance of immune tolerance. B7-2 is highly expressed on activated antigen presenting cells and vascular endothelial cells. It binds to CD28 on T cells to enhance T cell activation. It additionally binds CTLA-4 which inhibits the T cell response and supports regulatory T cell function. The relative participation of B7-1 and B7-2 in T cell co-stimulation can alter the Th1/Th2 bias of the immune response. Both B7-1 and B7-2 serve as cellular receptors for B species adenoviruses.

Show More

268 results for "B7-2/CD86" in Products

Back to Search Results
Apply

268 results for "B7-2/CD86" in Products

B7-2/CD86 Products

B7-2/CD86 and the related B7-1/CD80 are transmembrane cell surface molecules that play important roles in immune activation and the maintenance of immune tolerance. B7-2 is highly expressed on activated antigen presenting cells and vascular endothelial cells. It binds to CD28 on T cells to enhance T cell activation. It additionally binds CTLA-4 which inhibits the T cell response and supports regulatory T cell function. The relative participation of B7-1 and B7-2 in T cell co-stimulation can alter the Th1/Th2 bias of the immune response. Both B7-1 and B7-2 serve as cellular receptors for B species adenoviruses.

Show More
Applications: IHC, WB, ICC/IF, Flow, B/N, KO
Reactivity: Human, Mouse, Rat

Clone BU63 was used by HLDA to establish CD designation.

Applications: WB, IHC, KO, Neut
Reactivity: Human
Applications: WB, Flow, CyTOF-ready, KO, Neut
Reactivity: Human
Applications: Flow
Reactivity: Human
Applications: WB, Neut
Reactivity: Mouse
Applications: IHC, WB, ICC/IF, IP
Reactivity: Human, Mouse, Rat

Recombinant Monoclonal Antibody.

Applications: Flow
Reactivity: Human
Applications: IHC, ICC/IF, Flow, CyTOF-ready
Reactivity: Mouse
Applications: IHC
Reactivity: Mouse
Applications: WB, Flow, IHC, CyTOF-ready
Reactivity: Rat
Applications: Flow
Reactivity: Human
Applications: IHC, WB, ICC/IF, Flow, KO
Reactivity: Human, Mouse, Rat
Applications: WB, IHC, KO
Reactivity: Cynomolgus Monkey
Applications: WB, Flow, CyTOF-ready, Neut
Reactivity: Mouse
Applications: Flow
Reactivity: Human
Applications: BA, BA

Biotinylated

Applications: BA

Fc Chimera

Applications: IHC, ICC/IF
Reactivity: Human, Mouse, Rat
Applications: BA
Applications: WB, IHC
Reactivity: Rat
Applications: IHC
Reactivity: Human
Applications: BA

Fc Chimera

Applications: ELISA
Applications: WB
Reactivity: Human
Results Per Page
5 10 25 50
/ 11