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BMP-2 Products

BMP-2 (Bone morphogenetic protein 2) is a TGF-beta superfamily cytokine that plays a dominant role in embryonic dorsal-ventral patterning, organogenesis, limb bud formation, and bone formation and regeneration. BMP-2 forms disulfide linked homodimers and heterodimers with BMP-7. BMP-2 signals through heterodimeric complexes of type I receptors (ActiRI, BMPR-IA, or BMPR-IB) and type II receptors (BMP RII or ActRIIB).

It induces chondrocyte proliferation, endochondral bone formation, longitudinal bone growth, and bone and cartilage repair. BMP-2/BMP-7 heterodimers are significantly more potent than BMP-2 homodimers at inducing bone formation in vivo. BMP-2 also promotes the maintenance and repair of colonic epithelium, suppresses neuronal dopamine synthesis and release, induces apoptosis in medulloblastoma cells, and is required for cardiac contractility.

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142 results for "BMP-2" in Products

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142 results for "BMP-2" in Products

BMP-2 Products

BMP-2 (Bone morphogenetic protein 2) is a TGF-beta superfamily cytokine that plays a dominant role in embryonic dorsal-ventral patterning, organogenesis, limb bud formation, and bone formation and regeneration. BMP-2 forms disulfide linked homodimers and heterodimers with BMP-7. BMP-2 signals through heterodimeric complexes of type I receptors (ActiRI, BMPR-IA, or BMPR-IB) and type II receptors (BMP RII or ActRIIB).

It induces chondrocyte proliferation, endochondral bone formation, longitudinal bone growth, and bone and cartilage repair. BMP-2/BMP-7 heterodimers are significantly more potent than BMP-2 homodimers at inducing bone formation in vivo. BMP-2 also promotes the maintenance and repair of colonic epithelium, suppresses neuronal dopamine synthesis and release, induces apoptosis in medulloblastoma cells, and is required for cardiac contractility.

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Applications: Simple Plex
Applications: IHC, WB, ICC/IF
Reactivity: Human, Mouse, Rat, Canine
Applications: Simple Plex

Simple Plex Human BMP-2 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.

Applications: WB, Neut
Reactivity: Human
Applications: WB
Reactivity: Human
Applications: WB, IHC
Reactivity: Human
Applications: Ctrl

For use with catalog numbers DBP200, SBP200, PDBP200

Applications: WB, IHC
Reactivity: Human
Applications: WB
Reactivity: Human
Applications: WB, Neut
Reactivity: Zebrafish
Applications: WB, ICC
Reactivity: Human
Reactivity: Human
Applications: WB
Reactivity: Human
Applications: WB
Reactivity: Zebrafish
Applications: WB, ELISA, ICC/IF, Flow
Reactivity: Human
Applications: Ctrl, Simple Plex

Control for use with Human BMP-2 Simple Plex Cartridge Kit

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