Cannabinoid R1/CB1 Antagonists: Small Molecules and Peptides
Cannabinoid Receptors are seven-pass transmembrane proteins that belong to the rhodopsin family of G protein-coupled receptors. There are at least two types of Cannabinoid receptors, CB1R and CB2R, which are activated by a family of endogenous arachidonic acid derivatives, such as the endocannabinoids and D9-THC. CB1R is expressed in the central nervous system and upper GI tract, while CB2R is expressed by selected neuronal cell types and hematopoietic cells.
5 results for "Cannabinoid R1/CB1 Antagonists Small Molecules and Peptides" in Products
5 results for "Cannabinoid R1/CB1 Antagonists Small Molecules and Peptides" in Products
Cannabinoid R1/CB1 Antagonists: Small Molecules and Peptides
Cannabinoid Receptors are seven-pass transmembrane proteins that belong to the rhodopsin family of G protein-coupled receptors. There are at least two types of Cannabinoid receptors, CB1R and CB2R, which are activated by a family of endogenous arachidonic acid derivatives, such as the endocannabinoids and D9-THC. CB1R is expressed in the central nervous system and upper GI tract, while CB2R is expressed by selected neuronal cell types and hematopoietic cells.
Potent CB1 antagonist; also GPR55 agonist
| Chemical Name: | N-(Piperidin-1-yl)-5-(4-iodophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide |
| Purity: | ≥99% (HPLC) |
CB1 antagonist
| Chemical Name: | 1-[8-(2-Chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]-4-(ethylamino)piperidine-4-carboxamide hydrochloride |
| Purity: | ≥99% (HPLC) |
High affinity and selective CB1 antagonist
| Chemical Name: | 5-[4-(4-Cyano-1-butyn-1-yl)phenyl]-1-(2,4-dichlorophenyl)-N-(1,1-dioxido-4-thiomorpholinyl)-4-methyl-1H-pyrazole-3-carboxamide |
| Purity: | ≥98% (HPLC) |
Ultra-high affinity and selective CB1 antagonist
| Chemical Name: | 8-Chloro-1-(2,4-dichlorophenyl)-1,4,5,6-tetrahydro-N-1-piperidinyl-benzo[6,7]cyclohepta[1,2-c]pyrazole-3-carboxamide |
| Purity: | ≥98% (HPLC) |
High affinity and selective CB1 antagonist
| Chemical Name: | 5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide |
| Purity: | ≥98% |
