CLEC-2/CLEC1B Products
CLEC-2 (C-type lectin-like receptor 2), also known as CLEC-1B, is a transmembrane glycoprotein that is expressed on platelets, megakaryocyte, and liver sinusoidal cells. CLEC-2 binding to Podoplanin triggers platelet activation, shedding of GPVI, and cleavage of Fcgamma RIIA/CD32a. CLEC-2 expression on platelets is required for the development of lymphatic vessels and valves as well as the maintenance of lymph node high endothelial veinules (HEV) during lymphocyte crossing.
CLEC-2 additionally binds to fucoidan, HIV-1, and the platelet-aggregating snake venom protein Rhodocytin/Aggretin. In the liver, soluble CLEC-2 promotes M2 macrophage differentiation and limits inflammatory cytokine production.
Products:
72 results for "CLEC-2/CLEC1B" in Products
72 results for "CLEC-2/CLEC1B" in Products
CLEC-2/CLEC1B Products
CLEC-2 (C-type lectin-like receptor 2), also known as CLEC-1B, is a transmembrane glycoprotein that is expressed on platelets, megakaryocyte, and liver sinusoidal cells. CLEC-2 binding to Podoplanin triggers platelet activation, shedding of GPVI, and cleavage of Fcgamma RIIA/CD32a. CLEC-2 expression on platelets is required for the development of lymphatic vessels and valves as well as the maintenance of lymph node high endothelial veinules (HEV) during lymphocyte crossing.
CLEC-2 additionally binds to fucoidan, HIV-1, and the platelet-aggregating snake venom protein Rhodocytin/Aggretin. In the liver, soluble CLEC-2 promotes M2 macrophage differentiation and limits inflammatory cytokine production.
Products:
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Source: | NS0 |
| Accession #: | AAF36777 |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #219150 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #219133 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Source: | NS0 |
| Accession #: | Q9JL99 |
| Applications: | BA |
| Source: | CHO |
| Accession #: | Q9P126.2 |
| Applications: | BA |
Contains 4 membranes - each spotted in duplicate with 59 different immunoreceptor antibodies
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #AYP1 |
| Applications: | ICC/IF, Flow, IP, CyTOF-ready, Func |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #AYP2 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #1C10 |
| Applications: | WB, ELISA, IP |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ELISA |
![Western Blot: CLEC-2/CLEC-1B Antibody [NB100-93458]](https://resources.bio-techne.com/images/products/CLEC1B-Antibody-Western-Blot-NB100-93458-img0002.jpg "Western Blot: CLEC-2/CLEC-1B Antibody [NB100-93458]")
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: CLEC-2/CLEC-1B Antibody [NBP1-79203]](https://resources.bio-techne.com/images/products/CLEC1B-Antibody-Western-Blot-NBP1-79203-img0002.jpg "Western Blot: CLEC-2/CLEC-1B Antibody [NBP1-79203]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
![CLEC-2/CLEC-1B Antibody Immunohistochemistry-Paraffin: CLEC-2/CLEC-1B Antibody [NBP3-24748]](https://resources.bio-techne.com/images/products/nbp3-24748_rabbit-clec-2-clec-1b-pab-1912202316104644.jpg "Immunohistochemistry-Paraffin: CLEC-2/CLEC-1B Antibody [NBP3-24748]")
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #004 |
| Applications: | ELISA |
| Applications: | WB |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #004 |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #AYP2 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #AYP1 |
| Applications: | ICC/IF, Flow, IP, CyTOF-ready, Func |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #004 |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #AYP1 |
| Applications: | ICC/IF, Flow, IP, CyTOF-ready, Func |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #004 |
| Applications: | ELISA |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #004 |
| Applications: | ELISA |