CLEC10A/CD301 Products
CLEC10A, also known as MGL, CD301, DC-ASGPR, and HML, is a transmembrane C-type lectin family that is expressed on immature myleloid dendritic cells, Langerhans cells, and alternatively activated (tolerogenic) macrophages. It is upregulated on pro-inflammatory monocytes in obesity and promotes their trafficking to adipose tissue.
CLEC10A selectively binds and internalizes terminal nonsialylated GalNAc moieties on O-linked carbohydrates including the Tn carcinoma antigen and carbohydrates on some CD45 isoforms. It also binds the GP envelope glycoprotein on Marburg and Ebola viruses and enhances viral entry and infectivity. Human and rat carry a single gene for CLEC10A/MGL, while mouse has two closely related MGL1 and MGL2 genes.
Products:
114 results for "CLEC10A/CD301" in Products
114 results for "CLEC10A/CD301" in Products
CLEC10A/CD301 Products
CLEC10A, also known as MGL, CD301, DC-ASGPR, and HML, is a transmembrane C-type lectin family that is expressed on immature myleloid dendritic cells, Langerhans cells, and alternatively activated (tolerogenic) macrophages. It is upregulated on pro-inflammatory monocytes in obesity and promotes their trafficking to adipose tissue.
CLEC10A selectively binds and internalizes terminal nonsialylated GalNAc moieties on O-linked carbohydrates including the Tn carcinoma antigen and carbohydrates on some CD45 isoforms. It also binds the GP envelope glycoprotein on Marburg and Ebola viruses and enhances viral entry and infectivity. Human and rat carry a single gene for CLEC10A/MGL, while mouse has two closely related MGL1 and MGL2 genes.
Products:
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Flow, CyTOF-ready |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #744812 |
| Applications: | Flow, CyTOF-ready |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human, Canine |
| Details: | Mouse IgG1 Monoclonal Clone #125A10.03 |
| Applications: | IHC, WB, Flow, IP, Func |
![Immunohistochemistry: CLEC10A/CD301 Antibody (125A10.03) [DDX0010P-100]](https://resources.bio-techne.com/images/products/CLEC10A-CD301-Antibody-125A10-03-Immunohistochemistry-DDX0010P-100-img0009.jpg "Immunohistochemistry: CLEC10A/CD301 Antibody (125A10.03) [DDX0010P-100]")
| Source: | NS0 |
| Accession #: | Q8IUN9 |
| Applications: | Bind |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #744812 |
| Applications: | Flow |
| Reactivity: | Mouse |
| Details: | Rat IgG2A Monoclonal Clone #ER-MP23 |
| Applications: | IHC, Flow |
![Immunohistochemistry: CLEC10A/CD301 Antibody (ER-MP23) - BSA Free [NB100-64874]](https://resources.bio-techne.com/images/products/CLEC10A-CD301-Antibody-ER-MP23-Immunohistochemistry-NB100-64874-img0004.jpg "Immunohistochemistry: CLEC10A/CD301 Antibody (ER-MP23) - BSA Free [NB100-64874]")
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #744812 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #121A5.01 |
| Applications: | IHC, WB, Flow, IP, Func |
![Immunohistochemistry: CLEC10A/CD301 Antibody (121A5.01) [DDX0011P-100]](https://resources.bio-techne.com/images/products/CLEC10A-CD301-Antibody-121A5-01-Immunohistochemistry-DDX0011P-100-img0003.jpg "Immunohistochemistry: CLEC10A/CD301 Antibody (121A5.01) [DDX0011P-100]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Western Blot: CLEC10A/CD301 Antibody [NBP1-84591]](https://resources.bio-techne.com/images/products/CLEC10A-CD301-Antibody-Western-Blot-NBP1-84591-img0005.jpg "Western Blot: CLEC10A/CD301 Antibody [NBP1-84591]")
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #744812 |
| Applications: | Flow |
| Source: | CHO |
| Accession #: | NP_071788 |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #744812 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #744812 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #744812 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #744812 |
| Applications: | Flow |
Recombinant Monoclonal Antibody
| Reactivity: | Mouse |
| Details: | Rabbit IgG Monoclonal Clone #019 |
| Applications: | ELISA |
| Applications: | WB |
![Western Blot: CLEC10A/CD301 Overexpression Lysate [NBP2-11302]](https://resources.bio-techne.com/images/products/CD301-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-11302-img0001.jpg "Western Blot: CLEC10A/CD301 Overexpression Lysate [NBP2-11302]")
| Applications: | WB |
![Western Blot: CLEC10A/CD301 Overexpression Lysate [NBL1-09254]](https://resources.bio-techne.com/images/products/CD301-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-09254-img0002.jpg "Western Blot: CLEC10A/CD301 Overexpression Lysate [NBL1-09254]")
Recombinant Monoclonal Antibody
| Reactivity: | Mouse |
| Details: | Rabbit IgG Monoclonal Clone #019 |
| Applications: | ELISA |
| Applications: | AC |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #744812 |
| Applications: | Flow, CyTOF-ready |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #744812 |
| Applications: | Flow, CyTOF-ready |