CTLA-4 Products
CTLA-4/CD152 (Cytotoxic T-Lymphocyte Antigen 4) is a transmembrane T cell inhibitory molecule that is expressed as a covalent homodimer. CTLA-4 is recruited from intracellular vesicles to the immunological synapse beginning 1-2 days after T cell activation. It forms a linear lattice with B7-1 on APC, inducing negative regulatory signals and ending CD28-dependent T cell activation. Mice deleted for CTLA-4 develop lethal autoimmune reactions due to continued T cell activation and poor control by regulatory T cells which constitutively express CTLA-4.
9 results for "CTLA-4" in Products
9 results for "CTLA-4" in Products
CTLA-4 Products
CTLA-4/CD152 (Cytotoxic T-Lymphocyte Antigen 4) is a transmembrane T cell inhibitory molecule that is expressed as a covalent homodimer. CTLA-4 is recruited from intracellular vesicles to the immunological synapse beginning 1-2 days after T cell activation. It forms a linear lattice with B7-1 on APC, inducing negative regulatory signals and ending CD28-dependent T cell activation. Mice deleted for CTLA-4 develop lethal autoimmune reactions due to continued T cell activation and poor control by regulatory T cells which constitutively express CTLA-4.
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Flow, CyTOF-ready, ICC |
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #BNI3 |
| Applications: | IHC, ICC/IF, ELISA, Flow, IP |
![CTLA-4 Antibody (BNI3) ELISA: CTLA-4 Antibody (BNI3) [NB100-64849] -](https://resources.bio-techne.com/images/products/nb100-64849_mouse-monoclonal-ctla-4-antibody-bni3-2312025235988.jpg "ELISA: CTLA-4 Antibody (BNI3) [NB100-64849] -")
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #48815 |
| Applications: | WB |
| Reactivity: | Human, Mouse |
| Details: | Mouse Monoclonal Clone #37B3D8.2F2 |
| Applications: | WB |
![Western Blot: CTLA-4 Antibody (37B3D8.2F2)BSA Free [NBP2-31143]](https://resources.bio-techne.com/images/products/CTLA4-Antibody-37B3D8-2F2-Western-Blot-NBP2-31143-img0001.jpg "Western Blot: CTLA-4 Antibody (37B3D8.2F2)BSA Free [NBP2-31143]")
Recombinant Monoclonal Antibody
| Reactivity: | Mouse |
| Details: | Rabbit IgG Kappa Monoclonal Clone #9H10 |
| Applications: | WB, ELISA, Flow, B/N |
![ELISA: CTLA-4 Antibody (9H10) - Chimeric - Azide and BSA Free [NBP3-11966]](https://resources.bio-techne.com/images/products/CTLA-4-Antibody-9H10-Chimeric-ELISA-NBP3-11966-img0001.jpg "ELISA: CTLA-4 Antibody (9H10) - Chimeric - Azide and BSA Free [NBP3-11966]")
| Reactivity: | Mouse |
| Details: | Armenian Hamster IgG Monoclonal Clone #1B8 |
| Applications: | WB, ELISA, Flow, IP |
| Reactivity: | Mouse |
| Details: | Rat IgG2 Monoclonal Clone #RM0199-6G10 |
| Applications: | WB, Flow, CyTOF-ready, B/N |
Recombinant Monoclonal Antibody
| Reactivity: | Mouse |
| Details: | Armenian Hamster IgG Kappa Monoclonal Clone #9H10 |
| Applications: | WB, ELISA, Flow, B/N |